Kobayashi Nobuko, Hirooka Kazuyuki, Nitta Eri, Ukegawa Kaori, Tsujikawa Akitaka
Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, 761-0793, Japan.
Int Ophthalmol. 2018 Oct;38(5):1969-1976. doi: 10.1007/s10792-017-0685-1. Epub 2017 Aug 10.
This study investigated postoperative visual acuity and corneal higher-order aberrations following EX-PRESS or trabeculectomy.
Out of 56 eyes of 56 patients analyzed, 30 eyes were treated using trabeculectomy, while 26 eyes were treated with EX-PRESS. Visual acuity and corneal higher-order aberrations were analyzed in both groups before and at 2 weeks, 1, 2, and 3 months after the surgeries. Risk factors that could potentially influence corneal higher-order aberrations were evaluated.
Significant reductions in the IOP were observed at 3 months after the surgery in both groups. Although a significant decrease in the visual acuity (logMAR) was observed at 2 weeks after the surgery in both groups, at 1 month after the surgeries, there were no significant differences found for the vision as compared to the baseline. At each study visit in the trabeculectomy group, significantly higher corneal higher-order aberrations compared to baseline were noted. In the EX-PRESS group, however, these aberrations were no longer significantly different from the baseline at month 2 (P = 0.36). Analysis of the risk factors indicated that hypotony could influence corneal higher-order aberrations after surgery.
Corneal higher-order aberrations were significantly increased at 1 month after EX-PRESS treatment, with levels returning to baseline by 2 months. After trabeculectomy, however, corneal higher-order aberrations remained significantly increased at 3 months after the procedure.
本研究调查了EX-PRESS植入术或小梁切除术后的视力及角膜高阶像差。
在分析的56例患者的56只眼中，30只眼接受小梁切除术治疗，26只眼接受EX-PRESS植入术治疗。在手术前及术后2周、1个月、2个月和3个月对两组患者的视力和角膜高阶像差进行分析。评估可能影响角膜高阶像差的危险因素。
两组患者术后3个月眼压均显著降低。虽然两组患者术后2周时视力（logMAR）均显著下降，但术后1个月时，与基线相比视力无显著差异。在小梁切除术组的每次研究访视中，均发现角膜高阶像差较基线显著升高。然而，在EX-PRESS植入术组中，这些像差在术后2个月时与基线相比不再有显著差异（P = 0.36）。危险因素分析表明，低眼压可能影响术后角膜高阶像差。
EX-PRESS植入术后1个月角膜高阶像差显著增加，至2个月时恢复至基线水平。然而，小梁切除术后，术后3个月角膜高阶像差仍显著增加。
