Ghadirian E, Kongshavn P A
Parasite Immunol. 1986 Nov;8(6):663-7. doi: 10.1111/j.1365-3024.1986.tb00879.x.
Treatment with Corynebacterium parvum or BCG, or infection with live Listeria monocytogenes was found to protect mice against subsequent infection with Entamoeba histolytica. Complete protection was obtained in mice treated with 10(7) (colony forming units) of BCG but not with 10(5). Partial protection was achieved with 10(6) of BCG. These data provide evidence that non-specific immunity plays an important role in the host defense against amoebic infection.
已发现用短小棒状杆菌或卡介苗进行治疗,或感染单核细胞增生李斯特菌活菌,可保护小鼠免受随后溶组织内阿米巴的感染。用10⁷(菌落形成单位)卡介苗治疗的小鼠获得了完全保护,而用10⁵则未获得完全保护。用10⁶卡介苗可实现部分保护。这些数据证明非特异性免疫在宿主抗阿米巴感染防御中起重要作用。