Limbert Georges
National Centre for Advanced Tribology at Southampton (nCATS), Bioengineering Science Research Group, Faculty of Engineering and the Environment, University of Southampton, Southampton SO17 1BJ, UK.
Biomechanics and Mechanobiology Laboratory, Biomedical Engineering Division, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa.
Proc Math Phys Eng Sci. 2017 Jul;473(2203):20170257. doi: 10.1098/rspa.2017.0257. Epub 2017 Jul 26.
The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas.
本文的目的是对皮肤生物物理学的数学和计算建模的某些方面进行综述，特别关注基于非线性连续介质力学的本构理论，从弹性到滞弹性，包括生长，再到热弹性。还讨论了结合成像技术的微观结构和唯象学方法。最后，将介绍最近在皮肤皱纹方面的研究应用，以突出基于物理的皮肤建模在应对全球挑战（如人口老龄化以及相关的皮肤退化、疾病和创伤）方面的潜力。
