Wan Qingsong, Yang Shikun, Li Li, Chu Fenfen
a Department of Nephrology , The First Affiliated Hospital of the University of South China , Hengyang , Hunan Province , China.
b Department of Nephrology , The Third Xiangya Hospital of Central South University , Changsha , Hunan Province , China.
Ren Fail. 2017 Nov;39(1):613-622. doi: 10.1080/0886022X.2017.1361835.
Far infrared (FIR) therapy may have a beneficial effect on maturity and function of arteriovenous fistulas (AVFs) in hemodialysis (HD) patients. Therefore, we performed this pooled analysis to assess the protective effects of FIR therapy in HD patients.
The randomized controlled trials (RCTs) and quasi-RCTs of FIR therapy for HD patients were searched from multiple databases. Relevant studies were screened according to the predefined inclusion criteria. The meta-analyses were performed using RevMan 5.2 software (The Cochrane Collaboration, Oxford, UK).
Meta-analysis showed that FIR therapy could significantly increase the vascular access blood flow level (MD, 81.69 ml/min; 95% CI, 46.17-117.21; p < .001), AVFs diameter level (MD, 0.36 mm; 95% CI, 0.22-0.51; p < .001), and the primary AVFs patency (pooled risk ratio = 1.24; 95% CI, 1.12-1.37, p < .001). In addition, therapy with FIR ray radiation could decrease AVFs occlusion rates (pooled risk ratio = 0.20; 95% CI, 0.08-0.46; p < .001) and the level of needling pain (pooled risk ratio = 0.08; 95% CI, 0.06-0.10, p < .001).
FIR therapy can reduce AVFs occlusion rates and needling pain level, while significantly improve the level of vascular access blood flow, AVFs diameter and the primary AVFs patency.
远红外线(FIR)疗法可能对血液透析(HD)患者动静脉内瘘(AVF)的成熟和功能产生有益影响。因此,我们进行了这项汇总分析,以评估FIR疗法对HD患者的保护作用。
从多个数据库中检索关于HD患者FIR疗法的随机对照试验(RCT)和准RCT。根据预先定义的纳入标准筛选相关研究。使用RevMan 5.2软件(英国牛津Cochrane协作网)进行荟萃分析。
荟萃分析表明,FIR疗法可显著提高血管通路血流量水平(MD,81.69 ml/min;95%CI,46.17 - 117.21;p <.001)、AVF直径水平(MD,0.36 mm;95%CI,0.22 - 0.51;p <.001)以及初次AVF通畅率(合并风险比 = 1.24;95%CI,1.12 - 1.37,p <.001)。此外,FIR射线辐射治疗可降低AVF闭塞率(合并风险比 = 0.20;95%CI,0.08 - 0.46;p <.001)和穿刺疼痛水平(合并风险比 = 0.08;95%CI,0.06 - 0.10,p <.001)。
FIR疗法可降低AVF闭塞率和穿刺疼痛水平,同时显著提高血管通路血流量水平、AVF直径及初次AVF通畅率。