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消毒剂杀病毒活性的表面试验:疱疹病毒的初步研究

A surface test for virucidal activity of disinfectants: preliminary study with herpes virus.

作者信息

Tyler R, Ayliffe G A

出版信息

J Hosp Infect. 1987 Jan;9(1):22-9. doi: 10.1016/0195-6701(87)90090-9.

Abstract

A test was developed to assess the surface activity of disinfectants against dried viral preparations. In this preliminary study a variety of disinfectants was tested against herpes virus. The results showed that 2% alkaline glutaraldehyde and 70% ethanol or isopropanol were effective in 1 min. Hypochlorite solutions (2500 ppm av. Cl2) were effective in 5 min, but povidone-iodine (10%) was slower in action and a clear soluble phenol showed uncertain activity at 5 and 10 min. High concentrations of alcohols (above 95%), two quaternary ammonium compounds and 0.5% aqueous chlorhexidine showed little activity in 10 min.

摘要

开发了一种测试方法来评估消毒剂对干燥病毒制剂的表面活性。在这项初步研究中,对多种消毒剂进行了抗疱疹病毒测试。结果表明,2%碱性戊二醛和70%乙醇或异丙醇在1分钟内有效。次氯酸盐溶液(平均2500 ppm Cl2)在5分钟内有效,但聚维酮碘(10%)起效较慢,一种透明可溶性酚在5分钟和10分钟时活性不确定。高浓度酒精(高于95%)、两种季铵化合物和0.5%氯己定水溶液在10分钟内活性很小。

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