UGC Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Regional de Málaga/Universidad de Málaga, 29009 Malaga, Spain.
Centro de Investigación Biomédica en Red (CIBERDEM CB07/08/0019), Instituto de Salud Carlos III, 29009 Malaga, Spain.
Nutrients. 2017 Aug 15;9(8):877. doi: 10.3390/nu9080877.
The satiating effects of cow dairy have been thoroughly investigated; however, the effects of goat dairy on appetite have not been reported so far. Our study investigates the satiating effect of two breakfasts based on goat or cow dairy and their association with appetite related hormones and metabolic profile. Healthy adults consumed two breakfasts based on goat (G-Breakfast) or cow (C-Breakfast) dairy products. Blood samples were taken and VAS tests were performed at different time points. Blood metabolites were measured and Combined Satiety Index (CSI) and areas under the curves (AUC) were calculated. Desire to eat rating was significantly lower (breakfast & time interaction < 0.01) and hunger rating tended to be lower (breakfast & time interaction = 0.06) after the G-breakfast. None of the blood parameters studied were different between breakfasts; however, AUC was inversely associated with the AUC and AUC after the G-Breakfast, whereas triglyceride levels were directly associated with AUC after the C-Breakfast. Our results suggest a slightly higher satiating effect of goat dairy when compared to cow dairy products, and pointed to a potential association of GLP-1 and triglyceride levels with the mechanisms by which dairy products might affect satiety after the G-Breakfast and C-Breakfast, respectively.
牛乳制品的饱腹感作用已得到充分研究；然而，目前尚未有关于山羊乳制品对食欲影响的报道。我们的研究调查了基于山羊或牛奶的两种早餐的饱腹感作用及其与食欲相关激素和代谢特征的关系。健康成年人分别食用基于山羊（G 早餐）或牛奶（C 早餐）乳制品的两种早餐。在不同时间点采集血样并进行 VAS 测试。测量血液代谢物，并计算综合饱腹感指数（CSI）和曲线下面积（AUC）。G 早餐后，食欲评分明显降低（早餐和时间交互作用 < 0.01），饥饿评分也有降低的趋势（早餐和时间交互作用 = 0.06）。研究中没有一种血液参数在两种早餐之间存在差异；然而，AUC 与 G 早餐后的 AUC 和 AUC 呈负相关，而甘油三酯水平与 C 早餐后的 AUC 呈正相关。我们的研究结果表明，与牛奶乳制品相比，山羊乳制品的饱腹感作用略高，并且提示 GLP-1 和甘油三酯水平可能分别与 G 早餐和 C 早餐后乳制品影响饱腹感的机制有关。
