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基孔肯雅热:孟加拉国一种临床表现多样的新发病毒感染:7例报告

Chikungunya: an emerging viral infection with varied clinical presentations in Bangladesh: Reports of seven cases.

作者信息

Rahim Muhammad Abdur, Uddin Khwaja Nazim

机构信息

Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, 122 Kazi Nazrul Islam Avenue, Dhaka, Bangladesh.

出版信息

BMC Res Notes. 2017 Aug 15;10(1):410. doi: 10.1186/s13104-017-2723-5.

Abstract

BACKGROUND

Chikungunya is an emerging and rapidly spreading viral infection in many parts of the world including Bangladesh. It shares many epidemiological and clinical characteristics with dengue. So, a sound knowledge is required for its detection and differentiation from dengue, specially in endemic regions.

CASE PRESENTATION

We present seven confirmed cases of chikungunya having different clinical presentations occurring among middle aged males and females from different socio-economic background in Dhaka city, the capital of Bangladesh. All patients had fever and aches and pains. Less common features were rash, diarrhea, vomiting and altered liver biochemistry. Dengue was excluded in six patients. Paracetamol remained the mainstay of treatment during febrile periods, but over 50% of the patients had prolonged joint symptoms requiring non-steroidal anti-inflammatory drugs.

CONCLUSIONS

In spite of being a self-limiting disease, chikungunya may have different presentations and a protracted clinical course. During the febrile episode, exclusion of dengue is equally important. Physicians should be aware of the condition and public health initiatives are necessary to break the disease transmission.

摘要

背景

基孔肯雅热是一种在包括孟加拉国在内的世界许多地区新出现且迅速传播的病毒感染。它与登革热有许多流行病学和临床特征。因此,特别是在流行地区,需要具备扎实的知识来检测并将其与登革热区分开来。

病例报告

我们报告了7例确诊的基孔肯雅热病例,这些病例临床表现各异,发生在孟加拉国首都达卡市不同社会经济背景的中年男性和女性中。所有患者均有发热及疼痛。较少见的症状有皮疹、腹泻、呕吐及肝功能生化指标改变。6例患者排除了登革热。对乙酰氨基酚仍是发热期的主要治疗药物,但超过50%的患者有关节症状迁延,需要使用非甾体抗炎药。

结论

尽管基孔肯雅热是一种自限性疾病,但可能有不同表现及迁延的临床病程。在发热期,排除登革热同样重要。医生应了解这种疾病,并且需要采取公共卫生措施来阻断疾病传播。

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