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成人脊柱畸形融合手术中骨盆固定相关的30天发病率:一项倾向匹配分析

Thirty-Day Morbidity Associated with Pelvic Fixation in Adult Patients Undergoing Fusion for Spinal Deformity: A Propensity-Matched Analysis.

作者信息

Kothari Parth, Somani Sulaiman, Lee Nathan J, Guzman Javier Z, Leven Dante M, Skovrlj Branko, Steinberger Jeremy, Kim Jun, Cho Samuel K

机构信息

Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, United States.

Department of Orthopaedic Surgery, SUNY Health Science Center at Brooklyn, Brooklyn, New York, United States.

出版信息

Global Spine J. 2017 Feb;7(1):39-46. doi: 10.1055/s-0036-1583946. Epub 2017 Feb 1.

Abstract

STUDY DESIGN

Retrospective study of prospectively collected data.

OBJECTIVE

To determine if patients undergoing spinal deformity surgery with pelvic fixation are at an increased risk of morbidity.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program is a large multicenter clinical registry that prospectively collects preoperative risk factors, intraoperative variables, and 30-day postoperative morbidity and mortality outcomes from ~400 hospitals nationwide. Current Procedural Terminology codes were used to query the database between 2010 and 2014 for adults who underwent fusion for spinal deformity. Patients were separated into groups of those with and without pelvic fixation. Univariate analysis and multivariate logistic regression were used to analyze the effect of pelvic fixation on the incidence of postoperative morbidity and other surgical outcomes.

RESULTS

Multivariate analysis showed that pelvic fixation was a significant predictor of overall morbidity (odds ratio [OR] = 2.3, 95% confidence interval [CI]: 1.7 to 3.1, = 0.0002), intra- or postoperative blood transfusion (OR = 2.3, 95% CI: 1.7 to 3.1 < 0.0001), extended operative time (OR = 4.7, 95% CI: 3.1 to 7.0 < 0.0001), and length of stay > 5 days (OR = 2.1, 95% CI 1.5 to 2.8, < 0.0001) in patients undergoing fusion for spinal deformity. However, fusion to the pelvis did not lead to additional risk for other complications, including wound complications ( = 0.3191).

CONCLUSION

Adult patients undergoing spinal deformity surgery with pelvic fixation were not susceptible to increased morbidity beyond increased blood loss, greater operative time, and extended length of stay.

摘要

研究设计

对前瞻性收集的数据进行回顾性研究。

目的

确定接受脊柱畸形手术并进行骨盆固定的患者是否有更高的发病风险。

方法

美国外科医师学会国家外科质量改进计划是一个大型多中心临床登记系统,前瞻性收集全国约400家医院的术前危险因素、术中变量以及术后30天的发病和死亡结果。使用当前程序编码术语在2010年至2014年间查询数据库,以获取接受脊柱畸形融合手术的成年人信息。患者被分为有骨盆固定和无骨盆固定两组。采用单因素分析和多因素逻辑回归分析骨盆固定对术后发病率及其他手术结果的影响。

结果

多因素分析显示,骨盆固定是脊柱畸形融合手术患者总体发病率(优势比[OR]=2.3,95%置信区间[CI]:1.7至3.1,P = 0.0002)、术中或术后输血(OR = 2.3,95% CI:1.7至3.1,P < 0.0001)、手术时间延长(OR = 4.7,95% CI:3.1至7.0,P < 0.0001)以及住院时间>5天(OR = 2.1,95% CI 1.5至2.8,P < 0.0001)的显著预测因素。然而,融合至骨盆并未导致其他并发症的额外风险,包括伤口并发症(P = 0.3191)。

结论

接受脊柱畸形手术并进行骨盆固定的成年患者,除失血增加、手术时间延长和住院时间延长外,不易出现发病率增加的情况。

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