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Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression.

作者信息

Stevens Bruce R, Goel Ruby, Seungbum Kim, Richards Elaine M, Holbert Richard C, Pepine Carl J, Raizada Mohan K

机构信息

Department of Physiology & Functional Genomics, University of Florida College of Medicine, Gainesville, Florida, USA.

Department of Psychiatry, University of Florida College of Medicine, Gainesville, Florida, USA.

出版信息

Gut. 2018 Aug;67(8):1555-1557. doi: 10.1136/gutjnl-2017-314759. Epub 2017 Aug 16.

DOI:10.1136/gutjnl-2017-314759
PMID:28814485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5851874/
Abstract
摘要

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本文引用的文献

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2
Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases.闭合蛋白，一种上皮和内皮屏障功能的调节因子，及其在慢性炎症性疾病中的作用。
Tissue Barriers. 2016 Oct 21;4(4):e1251384. doi: 10.1080/21688370.2016.1251384. eCollection 2016.
3
Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil.巴西东北部儿童环境肠病、炎症、发育迟缓及生长障碍的生物标志物
PLoS One. 2016 Sep 30;11(9):e0158772. doi: 10.1371/journal.pone.0158772. eCollection 2016.
4
Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease.在无乳糜泻的情况下报告对小麦敏感的个体中肠道细胞损伤和全身免疫激活。
Gut. 2016 Dec;65(12):1930-1937. doi: 10.1136/gutjnl-2016-311964. Epub 2016 Jul 25.
5
Mood disturbance during experimental endotoxemia: Predictors of state anxiety as a psychological component of sickness behavior.实验性内毒素血症期间的情绪障碍：作为疾病行为的心理组成部分的状态焦虑的预测因子。
Brain Behav Immun. 2016 Oct;57:30-37. doi: 10.1016/j.bbi.2016.01.003. Epub 2016 Jan 11.
6
The gut microbiota and host health: a new clinical frontier.肠道微生物群与宿主健康：一个新的临床前沿领域。
Gut. 2016 Feb;65(2):330-9. doi: 10.1136/gutjnl-2015-309990. Epub 2015 Sep 2.
7
Dose-dependent effects of endotoxin on neurobehavioral functions in humans.内毒素对人类神经行为功能的剂量依赖性影响。
PLoS One. 2011;6(12):e28330. doi: 10.1371/journal.pone.0028330. Epub 2011 Dec 2.