接受抗逆转录病毒治疗的人类免疫缺陷病毒患者的结膜菌群
Conjunctival Flora of Human Immunodeficiency Virus Patients on Antiretroviral Treatment.
作者信息
Giles Kagmeni, Bilong Yannick, Dohvoma Andin Viola, Ebana Steve Robert, Gonsu Hortance
机构信息
University Teaching Hospital of Yaoundé (UTHY), Yaoundé, Cameroon.
Eye Department, University of Yaoundé I, Yaoundé, Cameroon.
出版信息
Ophthalmol Eye Dis. 2017 Aug 3;9:1179172117724760. doi: 10.1177/1179172117724760. eCollection 2017.
OBJECTIVES
To determine the conjunctival flora of human immunodeficiency virus (HIV) patients on antiretroviral treatment (ART).
METHODOLOGY
A total of 104 conjunctival swabs from 104 HIV patients on ART underwent microbiological evaluation to describe the flora.
RESULT
There were 71 (68.26%) women and 33 (31.74%) men. The mean age was 42.9 ± 9.77 (range: 22-70) years. Negative cultures were found in 39 (37.50%) cases. Bacterial growth occurred in 65 (62.50%) cases. Coagulase-negative was found in 59 eyes (90.76%), and coagulase-positive in 3 eyes (4.61%). There was a significant correlation between the duration of ART, the degrees of immunosuppression, and bacterial growth.
CONCLUSIONS
Knowledge of the conjunctival flora in HIV patients may provide a better guideline in the choice of antibiotic for the management of ocular surface infections.
目的
确定接受抗逆转录病毒治疗（ART）的人类免疫缺陷病毒（HIV）患者的结膜菌群。
方法
对104例接受ART的HIV患者的104份结膜拭子进行微生物学评估，以描述菌群情况。
结果
有71名（68.26%）女性和33名（31.74%）男性。平均年龄为42.9±9.77（范围：22 - 70）岁。39例（37.50%）培养结果为阴性。65例（62.50%）出现细菌生长。59只眼（90.76%）发现凝固酶阴性菌，3只眼（4.61%）发现凝固酶阳性菌。ART持续时间、免疫抑制程度与细菌生长之间存在显著相关性。
结论
了解HIV患者的结膜菌群可能为眼表感染管理中抗生素的选择提供更好的指导。
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