IEEE Rev Biomed Eng. 2017;10:122-135. doi: 10.1109/RBME.2017.2739801. Epub 2017 Aug 14.
Monte Carlo (MC) simulation for light propagation in tissue is the gold standard for studying the light propagation in biological tissue and has been used for years. Interaction of photons with a medium is simulated based on its optical properties. New simulation geometries, tissue-light interaction methods, and recording techniques recently have been designed. Applications, such as whole mouse body simulations for fluorescence imaging, eye modeling for blood vessel imaging, skin modeling for terahertz imaging, and human head modeling for sinus imaging, have emerged. Here, we review the technical advances and recent applications of MC simulation.
蒙特卡罗（MC）模拟在组织中的光传播是研究生物组织中光传播的黄金标准，已经使用了多年。光子与介质的相互作用是根据其光学特性进行模拟的。最近设计了新的模拟几何形状、组织-光相互作用方法和记录技术。已经出现了一些应用，例如用于荧光成像的整个老鼠身体模拟、用于血管成像的眼睛建模、用于太赫兹成像的皮肤建模以及用于窦成像的人头建模。在这里，我们回顾了 MC 模拟的技术进展和最近的应用。
