Fedtke Cathleen, Ehrmann Klaus, Thomas Varghese, Bakaraju Ravi C
1The Brien Holden Vision Institute, Sydney, New South Wales, Australia 2School of Optometry and Vision Science, The University of New South Wales, Sydney, New South Wales, Australia.
Optom Vis Sci. 2017 Sep;94(9):876-885. doi: 10.1097/OPX.0000000000001112.
The amount of central or peripheral myopic shift, as induced by different multifocal contact lenses when viewing objects at distance or near, may provide insights on the potential efficacy for slowing eye growth.
The present study aims to compare peripheral refraction and higher-order aberration profiles of four multifocal contact lenses with a single vision control lens.
Thirty-five myopes (age 21.2 ± 2.1 years) completed the trial, of whom 16 wore Air Optix Aqua and Proclear Multifocal Distance and Near (Group 1, spherical equivalent: -2.90 ± 0.95D), whereas 19 wore Air Optix Aqua, Air Optix Multifocal, and PureVision Multifocal (Group 2, spherical equivalent: -2.95 ± 0.78D). Refraction and aberration profiles with lenses were measured using the BHVI-EyeMapper with (-2.00 to -5.00D in 1.00D steps) and without (+1.00D fogging) accommodation. Data were quantified using M2/4 (2nd and 2nd + 4th order), J0, J45, and higher-order aberration coefficients coma C[3, 1] and spherical aberration C[4, 0].
The center-distance lens exhibited a relative peripheral myopic shift in M2/4 and J0, positive on-axis C[4, 0], negative on-axis C[3, 1] and on-axis M4 was less negative for accommodative demands ≤-3.00D (P < .05). Inversely, the center-near lenses showed a relative peripheral hyperopic shift in M2/4 and J0, negative on-axis C[4, 0], positive on-axis C[3, 1] and on-axis M4 was more negative for demands of -2.00 and -3.00D (P < .05). Independent of lens type, relative peripheral M4 significantly decreased during accommodation. Accounting for C[4, 0], a greater change in relative M profiles and accommodative responses was found for multifocal lenses.
Based on the hypothesis that myopic retinal defocus counters eye growth, center-near multifocal lenses exhibited the preferred on-axis features, i.e., producing a central myopic shift at near compared to the control. The center-distance lens exhibited preferred off-axis features, producing relative peripheral myopia, which increased further during accommodation.
不同多焦点隐形眼镜在看远或看近物体时所引起的中央或周边近视性偏移量，可能为减缓眼球生长的潜在效果提供见解。
本研究旨在比较四种多焦点隐形眼镜与单焦点对照镜片的周边屈光和高阶像差特征。
35名近视患者（年龄21.2±2.1岁）完成了试验，其中16人佩戴爱尔康水润型和博士伦多焦点远用及近用镜片（第1组，等效球镜度：-2.90±0.95D），而19人佩戴爱尔康水润型、爱尔康多焦点和视康多焦点镜片（第2组，等效球镜度：-2.95±0.78D）。使用BHVI-EyeMapper在调节状态下（以1.00D步长从-2.00到-5.00D）和非调节状态下（+1.00D雾视）测量镜片的屈光和像差特征。数据使用M2/4（二阶和二阶+四阶）、J0、J45以及高阶像差系数彗差C[3, 1]和球差C[4, 0]进行量化。
中央远距离镜片在M2/4和J0中表现出相对周边近视性偏移，轴上C[4, 0]为正，轴上C[3, 1]为负，且对于调节需求≤-3.00D时轴上M4的负值更小（P<.05）。相反，中央近距离镜片在M2/4和J0中表现出相对周边远视性偏移，轴上C[4, 0]为负，轴上C[3, 1]为正，且对于-2.00和-3.00D的需求时轴上M4的负值更大（P<.05）。与镜片类型无关，调节过程中相对周边M4显著降低。考虑C[4, 0]时，多焦点镜片在相对M特征和调节反应方面有更大变化。
基于近视性视网膜离焦对抗眼球生长的假设，中央近距离多焦点镜片表现出更优的轴上特征，即在近视力时与对照组相比产生中央近视性偏移。中央远距离镜片表现出更优的离轴特征，产生相对周边近视，在调节过程中进一步增加。
