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一种作为溶酶体追踪试剂和光动力治疗剂的近红外磷光锇(II)配合物。

A NIR phosphorescent osmium(ii) complex as a lysosome tracking reagent and photodynamic therapeutic agent.

作者信息

Zhang Pingyu, Wang Yi, Qiu Kangqiang, Zhao Zhiqian, Hu Rentao, He Chuanxin, Zhang Qianling, Chao Hui

机构信息

Shenzhen Key Laboratory of Functional Polymer, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.

出版信息

Chem Commun (Camb). 2017 Nov 14;53(91):12341-12344. doi: 10.1039/c7cc07776a.

Abstract

A novel near infrared (NIR) phosphorescent osmium complex (Os1) was developed for lysosome tracking and photodynamic therapy. Owing to its NIR photophysical properties, cellular imaging ability and phototoxicity, it has advantages over its ruthenium analogue (Ru1).

摘要

一种新型近红外(NIR)磷光锇配合物(Os1)被开发用于溶酶体追踪和光动力疗法。由于其近红外光物理性质、细胞成像能力和光毒性,它比其钌类似物(Ru1)具有优势。

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