与使用长波红外热成像技术的对照受试者相比，伤口感染和炎症中的相对温度最大值。

Relative Temperature Maximum in Wound Infection and Inflammation as Compared with a Control Subject Using Long-Wave Infrared Thermography.

作者信息

Chanmugam Arjun, Langemo Diane, Thomason Korissa, Haan Jaimee, Altenburger Elizabeth A, Tippett Aletha, Henderson Linda, Zortman Todd A

机构信息

Arjun Chanmugam, MD, MBA, is Professor and Vice Chair, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Diane Langemo, PhD, RN, FAAN, is President, Langemo & Associates, and Professor Emeritus and Adjunct Professor, University of North Dakota College of Nursing, Grand Forks. Korissa Thomason, MS, BSSN, RN, is Consultant, EHOB, Inc, Indianapolis, Indiana. Jaimee Haan, PT, CWS, is Program Manager, Physical Therapy Wound Management, Rehabilitation Services, Indiana University Health, Indianapolis. Elizabeth A. Altenburger, PT, MSPT, CWS, is Team Leader, Physical Therapy Wound Team, Indiana University Health Methodist Wound Center, Indianapolis. Aletha Tippett, MD, is Medical Director, Brookdale Hospice, Dayton, Ohio. Linda Henderson, BSN, RN, is Vice President of Clinical Services, CareGivers, Inc, Indianapolis, Indiana. Todd Zortman, RN, is Wound Care Coordinator at the Rehab Hospital of Indiana, Indianapolis. Dr Chanmugam has disclosed that he was remunerated by WoundVision for travel related to the study and the provision of writing assistance, medicines, equipment, or administrative support. Dr. Langemo has disclosed that she is remunerated by WoundVision for her consulting/writing/reviewing services. The authors have disclosed they have no other financial relationships related to this article. Acknowledgments: Training and assistance with image thermal analysis were provided by WoundVision. Submitted July 13, 2016; accepted in revised form October 28, 2016.

出版信息

Adv Skin Wound Care. 2017 Sep;30(9):406-414. doi: 10.1097/01.ASW.0000522161.13573.62.

DOI:10.1097/01.ASW.0000522161.13573.62

PMID:28817451

Abstract

OBJECTIVE

The purpose of this retrospective case series was to determine whether a long-wave infrared thermography (LWIT, or thermal imaging) camera can detect specific temperature changes that are associated with wound infection and inflammation as compared with normal control subjects with similar anatomical wound locations.

DESIGN

A retrospective, observational, collective, multiple case series of patients who underwent digital and thermal imaging of wounds in various states.

SETTING

The subjects were selected from multiple sites including an outpatient wound care clinic, a wound care physician's office, a rehabilitation hospital, and a home healthcare organization.

PATIENTS

Six subjects were selected for inclusion, including 2 each for the infection, inflammation, and normal control groups.

MAIN OUTCOME MEASURE

The study collected relative temperature maximums as obtained and recorded by LWIT and digital imaging.

MAIN RESULTS

In this case series, the authors demonstrate the use of an FDA-approved Scout (WoundVision, Indianapolis, Indiana) dual-imaging long-wave infrared and digital cameras to analyze images of wounds. In the 2 cases with clinically diagnosed wound infection, LWIT showed an elevation of temperature as evidenced by a maximum temperature differential between the wound and healthy skin of +4° C to 5° C. Also, LWIT was able to identify relative thermal changes of +1.5° C to 2.2° C in subjects presenting with clinical signs of inflammation. In addition, LWIT was able to show that the normal control subjects without diagnosis of infection or signs of inflammation had relative temperature differentials of +1.1° C to 1.2° C. Finally, LWIT could detect adequate treatment of infected wounds with antibiotics as evidenced by a return to normal temperature differences gradient of +0.8° C to 1.1° C, as compared with normal control subjects with wounds in the same anatomical location.

CONCLUSIONS

Long-wave infrared thermography can collect and record objective data, including relative temperature maximums associated with infection, inflammation, and normal healing wounds.

摘要

目的

本回顾性病例系列研究的目的是确定与具有相似解剖伤口位置的正常对照受试者相比，长波红外热成像（LWIT，即热成像）相机能否检测出与伤口感染和炎症相关的特定温度变化。

设计

对处于不同状态伤口的患者进行数字和热成像检查的回顾性、观察性、汇总性多病例系列研究。

地点

受试者选自多个地点，包括门诊伤口护理诊所、伤口护理医生办公室、康复医院和家庭医疗保健机构。

患者

选取6名受试者纳入研究，感染组、炎症组和正常对照组各2名。

主要观察指标

本研究收集了LWIT和数字成像获取并记录的相对温度最大值。

主要结果

在本病例系列中，作者展示了使用美国食品药品监督管理局（FDA）批准的Scout（WoundVision公司，印第安纳波利斯，印第安纳州）双成像长波红外和数字相机分析伤口图像的情况。在2例临床诊断为伤口感染的病例中，LWIT显示温度升高，伤口与健康皮肤之间的最大温差为+4℃至5℃。此外，LWIT能够识别出有临床炎症体征的受试者中+1.5℃至2.2℃的相对热变化。此外，LWIT能够显示未诊断出感染或炎症体征的正常对照受试者的相对温差为+1.1℃至1.2℃。最后，与相同解剖位置有伤口的正常对照受试者相比，LWIT能够检测出用抗生素治疗感染伤口后温度差异梯度恢复到+0.8℃至1.1℃，证明感染伤口得到了充分治疗。