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疱疹病毒如何传递其基因组。

How herpesviruses pass on their genomes.

作者信息

Serquiña Anna K, Ziegelbauer Joseph M

机构信息

National Institutes of Health, Bethesda, MD.

National Institutes of Health, Bethesda, MD

出版信息

J Cell Biol. 2017 Sep 4;216(9):2611-2613. doi: 10.1083/jcb.201708077. Epub 2017 Aug 17.

Abstract

Herpesvirus genomes exist and replicate as episomes inside the host cell nucleus during latent infection. Chiu et al. (2017. https://doi.org/10.1083/jcb.201702013) find that unlike Epstein-Barr virus, which partitions viral genomes faithfully during cell division, Kaposi's Sarcoma-associated herpesvirus clusters viral genomes into loci that are distributed unequally to daughter cells.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccbe/5584196/bfc520249c08/JCB_201708077_Fig1.jpg

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