在非流行地区用于诊断慢性恰加斯病的快速诊断检测（赛普拉斯恰加斯快速检测）的准确性：一项回顾性纵向研究
Accuracy of a Rapid Diagnostic Test (Cypress Chagas Quick Test) for the Diagnosis of Chronic Chagas Disease in a Nonendemic Area: A Retrospective Longitudinal Study.
作者信息
Angheben Andrea, Staffolani Silvia, Anselmi Mariella, Tais Stefano, Degani Monica, Gobbi Federico, Buonfrate Dora, Gobbo Maria, Bisoffi Zeno
机构信息
Centro per le Malattie Tropicali, Ospedale Classificato Equiparato Sacro Cuore, Negrar, Verona, Italy.
Dipartimento di Scienze Biomediche e Salute Pubblica, Clinica di Malattie Infettive, Università Politecnica delle Marche, Ancona, Italy.
出版信息
Am J Trop Med Hyg. 2017 Nov;97(5):1486-1488. doi: 10.4269/ajtmh.17-0205. Epub 2017 Aug 18.
Abstract
We analyzed the accuracy of Chagas Quick Test, a rapid diagnostic test, for the diagnosis of chronic Chagas disease through a retrospective study on a cohort of 669 patients consecutively examined at a single reference center in Italy, during a 7-year period. We observed high concordance with serological reference standard but low accuracy for screening purposes (sensitivity/specificity: 82.8%/98.7%) at least in our nonendemic context.
摘要
我们通过一项回顾性研究，分析了快速诊断检测方法“查加斯快速检测”（Chagas Quick Test）在诊断慢性查加斯病方面的准确性。该研究针对意大利一家参考中心在7年期间连续检查的669名患者队列展开。我们观察到，该检测与血清学参考标准高度一致，但至少在我们的非流行环境中，用于筛查目的时准确性较低（灵敏度/特异性：82.8%/98.7%）。
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2
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