a Department of Community Health and Preventive Medicine , Morehouse School of Medicine , Atlanta , GA , USA.
b Department of Medicine , Vanderbilt University , Nashville , TN , USA.
Ethn Health. 2019 Aug;24(6):679-693. doi: 10.1080/13557858.2017.1367762. Epub 2017 Aug 22.
African Americans (AAs) are less likely to participate in cancer clinical trials (CCTs) despite experiencing disproportionately higher rates of cancer mortality. As a way to address these ongoing disparities, this study sought to qualitatively explore informational needs regarding CCTs among AA women and identify message considerations for educational information targeting AA women and their community. Three focus groups were conducted in which AA women viewed a DVD created as a decisional tool for CCT participation and provided feedback regarding content. Results indicated general fear regarding CCTs, which is partially attributable to the impact of historic research abuses, lack of information regarding CCTs, and lack of cultural relevance of the education and outreach materials for AA communities. Recruitment of AAs to CCTs may be enhanced by educational and outreach approaches that increase awareness of CCTs as well as involvement of the AA community in developing such interventions. Interventions should include the perspectives of AA women, as key stakeholders and decision-makers for their family and provide research information in a multimedia format that will facilitate family discussion and decision-making regarding CCTs.
非裔美国人（AA）参与癌症临床试验（CCT）的可能性较低，尽管他们的癌症死亡率不成比例地更高。为了解决这些持续存在的差距，本研究旨在定性探讨 AA 女性对 CCT 的信息需求，并确定针对 AA 女性及其社区的教育信息的信息考虑因素。进行了三次焦点小组讨论，AA 女性观看了一部作为 CCT 参与决策工具的 DVD，并就内容提供了反馈。结果表明，一般对 CCT 感到恐惧，这部分归因于历史研究滥用的影响、缺乏关于 CCT 的信息，以及针对 AA 社区的教育和外展材料缺乏文化相关性。通过提高对 CCT 的认识以及让 AA 社区参与制定此类干预措施，可能会增加 AA 参与 CCT 的机会。干预措施应包括 AA 女性的观点，因为她们是家庭的重要利益相关者和决策者，并以多媒体形式提供研究信息，以促进家庭讨论和决策 CCT。
