Benito Javier, Monteiro Beatriz P, Beauchamp Guy, Lascelles B Duncan X, Steagall Paulo V
J Am Vet Med Assoc. 2017 Sep 1;251(5):544-551. doi: 10.2460/javma.251.5.544.
OBJECTIVE To evaluate agreement between observers with different training and experience for assessment of postoperative pain and sedation in cats by use of a dynamic and interactive visual analog scale (DIVAS) and for assessment of postoperative pain in the same cats with a multidimensional composite pain scale (MCPS). DESIGN Randomized, controlled, blinded study. ANIMALS 45 adult cats undergoing ovariohysterectomy. PROCEDURES Cats received 1 of 3 preoperative treatments: bupivacaine, IP; meloxicam, SC with saline (0.9% NaCl) solution, IP, (positive control); or saline solution only, IP (negative control). All cats received premedication with buprenorphine prior to general anesthesia. An experienced observer (observer 1; male; native language, Spanish) used scales in English, and an inexperienced observer (observer 2; female; native language, French) used scales in French to assess signs of sedation and pain. Rescue analgesia was administered according to MCPS scoring by observer 1. Mean pain and sedation scores per treatment and time point, proportions of cats in each group with MCPS scores necessitating rescue analgesia, and mean MCPS scores assigned at the time of rescue analgesia were compared between observers. Agreement was assessed by intraclass correlation coefficient determination. Percentage disagreement between observers on the need for rescue analgesia was calculated. RESULTS Interobserver agreements for pain scores were good, and that for sedation scores was fair. On the basis of observer 1's MCPS scores, a greater proportion of cats in the negative control group received rescue analgesia than in the bupivacaine or positive control groups. Scores from observer 2 indicated a greater proportion of cats in the negative control group than in the positive control group required rescue analgesia but identified no significant difference between the negative control and bupivacaine groups for this variable. Overall, disagreement regarding need for rescue analgesia was identified for 22 of 360 (6.1%) paired observations. CONCLUSIONS AND CLINICAL RELEVANCE Interobserver differences in assessing pain can lead to different conclusions regarding treatment effectiveness.
目的 通过使用动态交互式视觉模拟评分法(DIVAS)评估不同训练和经验的观察者对猫术后疼痛和镇静的评估一致性,并使用多维综合疼痛量表(MCPS)评估同一批猫的术后疼痛。设计 随机、对照、盲法研究。动物 45 只接受卵巢子宫切除术的成年猫。步骤 猫接受 3 种术前治疗中的 1 种:布比卡因,腹腔注射;美洛昔康,皮下注射并用生理盐水(0.9%氯化钠)溶液腹腔注射(阳性对照);或仅用生理盐水溶液腹腔注射(阴性对照)。所有猫在全身麻醉前均接受丁丙诺啡预处理。一位经验丰富的观察者(观察者 1;男性;母语为西班牙语)使用英文量表,一位经验不足的观察者(观察者 2;女性;母语为法语)使用法语文量表评估镇静和疼痛体征。观察者 1 根据 MCPS 评分给予解救镇痛。比较观察者之间每种治疗和时间点的平均疼痛和镇静评分、每组中因 MCPS 评分需要解救镇痛的猫的比例以及解救镇痛时指定的平均 MCPS 评分。通过组内相关系数测定评估一致性。计算观察者之间在是否需要解救镇痛方面的分歧百分比。结果 观察者之间在疼痛评分上的一致性良好,在镇静评分上的一致性一般。根据观察者 1 的 MCPS 评分,阴性对照组中接受解救镇痛的猫的比例高于布比卡因组或阳性对照组。观察者 2 的评分表明,阴性对照组中需要解救镇痛的猫的比例高于阳性对照组,但在该变量上未发现阴性对照组和布比卡因组之间有显著差异。总体而言,在 360 对观察结果中有 22 对(6.1%)在是否需要解救镇痛方面存在分歧。结论与临床意义 观察者在评估疼痛方面的差异可能导致关于治疗效果的不同结论。