a Department of Neuroradiology, CHU Reims , University Reims-Champagne-Ardenne , Reims , France.
Expert Rev Neurother. 2017 Oct;17(10):977-986. doi: 10.1080/14737175.2017.1371593. Epub 2017 Sep 6.
Unruptured intracranial aneurysms (UIA) have a high prevalence (3.2%) and are increasingly diagnosed with modern imaging tools. The main risk of UIA is their rupture associated with intracranial bleeding with often severe clinical consequences. Areas covered: This review discusses the management strategy of UIAs, based on the large series of the literature (ISUIA, ATENA, UCAS, …), knowing that no randomized controlled trial is available to compare different strategies. The different endovascular treatments are described. Expert commentary: Due to the relatively scarce data regarding the risk of rupture of UIAs, the strategy of management is often difficult to define. It has to be multidisciplinary and has to take into account several factors related to the patient and the aneurysm. Beside the surgical approach, several endovascular tools are available to treat UIAs, that includes standard coiling, balloon-assisted coiling, stent-assisted coiling, flow diversion, and flow disruption.
未破裂颅内动脉瘤(UIA)的患病率较高(3.2%),并且随着现代成像工具的应用,其检出率也在不断增加。UIA 的主要风险是其破裂导致颅内出血,常伴有严重的临床后果。
本文根据大量文献(ISUIA、ATENA、UCAS 等)讨论了 UIA 的治疗策略,因为目前尚无随机对照试验可以比较不同的治疗策略。本文还描述了不同的血管内治疗方法。
由于关于 UIA 破裂风险的数据相对较少,因此管理策略的制定往往较为困难。这种策略需要多学科共同参与,并考虑与患者和动脉瘤相关的多个因素。除了手术方法,还有多种血管内工具可用于治疗 UIA,包括标准的线圈栓塞、球囊辅助线圈栓塞、支架辅助线圈栓塞、血流导向装置和血流阻断装置。