Martini Larissa C, Barbosa Neto Jair B, Petreche Beatriz, Fonseca Ana O, Santos Fernanda V Dos, Magalhães Lílian, Marques Alessandra G, Soares Camila, Cordeiro Quirino, Attux Cecília, Bressan Rodrigo A
Departamento de Psiquiatria, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Departamento de Medicina, Universidade Federal de São Carlos (UFSCar), São Carlos, SP, Brazil.
Braz J Psychiatry. 2018 Jan-Mar;40(1):35-40. doi: 10.1590/1516-4446-2016-2128. Epub 2017 Aug 21.
Work is considered one of the main forms of social organization; however, few individuals with schizophrenia find work opportunities. The purpose of this study was to evaluate the relationship between schizophrenia symptoms and job acquisition.
Fifty-three individuals diagnosed with schizophrenia from an outpatient treatment facility were included in an 18-month follow-up study. After enrollment, they participated in a prevocational training group. At the end of training (baseline) and 18 months later, sociodemographic, clinical data and occupational history were collected. Positive and negative symptoms (Positive and Negative Syndrome Scale - PANSS), depression (Calgary Depression Scale), disease severity (Clinical Global Impression - CGI), functionality (Global Assessment of Functioning - GAF), personal and social performance (Personal and Social Performance - PSP) and cognitive functions (Measurement and Treatment Research to Improve Cognition in Schizophrenia - MATRICS battery) were applied at baseline and at the end of the study.
Those with some previous work experience (n=19) presented lower scores on the PANSS, Calgary, GAF, CGI and PSP scales (p < 0.05) than those who did not work. Among those who worked, there was a slight worsening in positive symptoms (positive PANSS).
Individuals with less severe symptoms were more able to find employment. Positive symptom changes do not seem to affect participation at work; however, this calls for discussion about the importance of employment support.
工作被视为社会组织的主要形式之一；然而，很少有精神分裂症患者能找到工作机会。本研究的目的是评估精神分裂症症状与就业情况之间的关系。
来自门诊治疗机构的53名被诊断为精神分裂症的个体纳入了一项为期18个月的随访研究。入组后，他们参加了职业前培训小组。在培训结束时（基线）和18个月后，收集社会人口统计学、临床数据和职业史。在基线和研究结束时应用阳性和阴性症状（阳性和阴性症状量表 - PANSS）、抑郁（卡尔加里抑郁量表）、疾病严重程度（临床总体印象 - CGI）、功能（功能总体评估 - GAF）、个人和社会表现（个人和社会表现 - PSP）以及认知功能（改善精神分裂症认知的测量与治疗研究 - MATRICS电池组）。
有一些既往工作经验的人（n = 19）在PANSS、卡尔加里、GAF、CGI和PSP量表上的得分（p < 0.05）低于未工作的人。在工作的人中，阳性症状（阳性PANSS）略有恶化。
症状较轻的个体更有能力找到工作。阳性症状的变化似乎不影响工作参与；然而，这需要讨论就业支持的重要性。
