Kinoshita Yoshihiro, Furukawa Toshi A, Kinoshita Kuni, Honyashiki Mina, Omori Ichiro M, Marshall Max, Bond Gary R, Huxley Peter, Amano Naoji, Kingdon David
Department of Psychiatry, Shinshu University School of Medicine, Matsumoto, Japan.
Cochrane Database Syst Rev. 2013 Sep 13;2013(9):CD008297. doi: 10.1002/14651858.CD008297.pub2.
People who suffer from severe mental disorder experience high rates of unemployment. Supported employment is an approach to vocational rehabilitation that involves trying to place clients in competitive jobs without any extended preparation. The Individual placement and support (IPS) model is a carefully specified form of supported employment.
We searched the Cochrane Schizophrenia Group Trials Register (February 2010), which is compiled by systematic searches of major databases, handsearches and conference proceedings.
All relevant randomised clinical trials focusing on people with severe mental illness, of working age (normally 16 to 70 years), where supported employment was compared with other vocational approaches or treatment as usual. Outcomes such as days in employment, job stability, global state, social functioning, mental state, quality of life, satisfaction and costs were sought.
Two review authors (YK and KK) independently extracted data. For binary outcomes, we calculated risk ratio (RR) and its 95% confidence interval (CI), on an intention-to-treat basis. For continuous data, we estimated mean difference (MD) between groups and its 95% (CI). We employed a fixed-effect model for analyses. A random-effects model was also employed where heterogeneity was present.
A total of 14 randomised controlled trials were included in this review (total 2265 people). In terms of our primary outcome (employment: days in competitive employment, over one year follow-up), supported employment seems to significantly increase levels of any employment obtained during the course of studies (7 RCTs, n = 951, RR 3.24 CI 2.17 to 4.82, very low quality of evidence). Supported employment also seems to increase length of competitive employment when compared with other vocational approaches (1 RCT, n = 204, MD 70.63 CI 43.22 to 94.04, very low quality evidence). Supported employment also showed some advantages in other secondary outcomes. It appears to increase length (in days) of any form of paid employment (2 RCTs, n = 510, MD 84.94 CI 51.99 to 117.89, very low quality evidence) and job tenure (weeks) for competitive employment (1 RCT, n = 204, MD 9.86 CI 5.36 to 14.36, very low quality evidence) and any paid employment (3 RCTs, n = 735, MD 3.86 CI -2.94 to 22.17, very low quality evidence). Furthermore, one study indicated a decreased time to first competitive employment in the long term for people in supported employment (1 RCT, n = 204, MD -161.60 CI -225.73 to -97.47, very low quality evidence). A large amount of data were considerably skewed, and therefore not included in meta-analysis, which makes any meaningful interpretation of the vast amount of data very difficult.
AUTHORS' CONCLUSIONS: The limited available evidence suggests that supported employment is effective in improving a number of vocational outcomes relevant to people with severe mental illness, though there appears to exist some overall risk of bias in terms of the quality of individual studies. All studies should report a standard set of vocational and non-vocational outcomes that are relevant to the consumers and policy-makers. Studies with longer follow-up should be conducted to answer or address the critical question about durability of effects.
患有严重精神障碍的人群失业率很高。支持性就业是一种职业康复方法,包括尝试让客户在没有任何长期准备的情况下获得有竞争力的工作。个体安置与支持(IPS)模式是一种经过精心规定的支持性就业形式。
我们检索了Cochrane精神分裂症组试验注册库(2010年2月),该注册库通过对主要数据库、手工检索和会议记录进行系统检索编制而成。
所有针对工作年龄(通常为16至70岁)的严重精神疾病患者的相关随机临床试验,其中将支持性就业与其他职业方法或常规治疗进行比较。寻求就业天数、工作稳定性、整体状况、社会功能、精神状态、生活质量、满意度和成本等结果。
两位综述作者(YK和KK)独立提取数据。对于二分类结果,我们在意向性分析的基础上计算风险比(RR)及其95%置信区间(CI)。对于连续性数据,我们估计组间平均差(MD)及其95%(CI)。我们采用固定效应模型进行分析。在存在异质性的情况下也采用随机效应模型。
本综述共纳入14项随机对照试验(共2265人)。就我们的主要结果(就业:有竞争力的就业天数,一年以上随访)而言,支持性就业似乎能显著提高研究期间获得的任何就业水平(7项随机对照试验,n = 951,RR 3.24,CI 2.17至4.82,证据质量极低)。与其他职业方法相比,支持性就业似乎也能增加有竞争力的就业时长(1项随机对照试验,n = 204,MD 70.63,CI 43.22至94.04,证据质量极低)。支持性就业在其他次要结果方面也显示出一些优势。它似乎能增加任何形式有偿就业的时长(天数)(2项随机对照试验,n = 510,MD 84.94,CI 51.99至117.89,证据质量极低)以及有竞争力就业的工作任期(周数)(1项随机对照试验,n = 204,MD 9.86,CI 5.36至14.36,证据质量极低)和任何有偿就业的工作任期(3项随机对照试验,n = 735,MD 3.86,CI -2.94至22.17,证据质量极低)。此外,一项研究表明,从长期来看,接受支持性就业的人群首次获得有竞争力就业的时间缩短(1项随机对照试验,n = 204,MD -161.60,CI -225.73至 -97.47,证据质量极低)。大量数据严重偏态分布,因此未纳入荟萃分析,这使得对大量数据进行任何有意义的解释都非常困难。
现有有限证据表明,支持性就业在改善与严重精神疾病患者相关的一些职业结果方面是有效的,尽管就个体研究质量而言似乎存在一些总体偏倚风险。所有研究都应报告一套与消费者和政策制定者相关的标准职业和非职业结果。应开展随访时间更长的研究,以回答或解决关于效果持续性的关键问题。