Bell G D, Bown S, Morden A, Coady T, Logan R F
Lancet. 1987 May 2;1(8540):1022-4. doi: 10.1016/s0140-6736(87)92282-3.
Hypoxaemia during oesophagogastroduodenoscopy is well documented and contributes to cardiac arrhythmias and occasional deaths from endoscopy. In 50 patients sedated with intravenous midazolam and examined with a large-diameter endoscope, oxygen desaturation was abolished by giving oxygen (2 litres/min) by way of nasal cannulae throughout the procedure.
食管胃十二指肠镜检查期间的低氧血症已有充分记录，它会导致心律失常，并偶尔引发内镜检查相关的死亡。在50例接受静脉注射咪达唑仑镇静并使用大口径内镜进行检查的患者中，通过在整个操作过程中经鼻导管给予氧气（2升/分钟），氧饱和度下降得以消除。
