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是否有可能预测英国获得性免疫缺陷综合征(艾滋病)疫情的最小规模?

Is it possible to predict the minimum size of the acquired immunodeficiency syndrome (AIDS) epidemic in the United Kingdom?

作者信息

Anderson R M, Medley G F, Blythe S P, Johnson A M

出版信息

Lancet. 1987 May 9;1(8541):1073-5. doi: 10.1016/s0140-6736(87)90493-4.

DOI:10.1016/s0140-6736(87)90493-4
PMID:2883405
Abstract

A mathematical model of the dynamics of transmission of human immunodeficiency virus within the male homosexual population in the United Kingdom demonstrates that even the minimum size of the acquired immunodeficiency syndrome (AIDS) epidemic in the United Kingdom (based upon the assumption that all transmission ceased at the end of 1986) is difficult to predict. Model predictions are particularly sensitive to assumptions about the distributed incubation period of the disease, differences in frequency and patterns of sexual activity, and the proportion of infected people in whom AIDS later develops. More accurate predictions will depend on the collection of data on the incubation period of the disease, the infectiousness of infected persons, and on the numbers of new sexual partners of each sex per person and the duration of each partnership.

摘要

一个关于人类免疫缺陷病毒在英国男性同性恋人群中传播动态的数学模型表明,即便要预测英国后天免疫机能丧失综合症(艾滋病)流行的最小规模(基于所有传播在1986年底停止这一假设)也很困难。模型预测对有关该疾病分布潜伏期的假设、性活动频率和模式的差异以及后来发展成艾滋病的感染者比例特别敏感。更准确的预测将取决于收集有关该疾病潜伏期、感染者传染性的数据,以及取决于每个人不同性别的新性伴侣数量和每次性伴侣关系的持续时间。

相似文献

1
Is it possible to predict the minimum size of the acquired immunodeficiency syndrome (AIDS) epidemic in the United Kingdom?是否有可能预测英国获得性免疫缺陷综合征(艾滋病)疫情的最小规模?
Lancet. 1987 May 9;1(8541):1073-5. doi: 10.1016/s0140-6736(87)90493-4.
2
The transmission dynamics of the human immunodeficiency virus type 1 in the male homosexual community in the United Kingdom: the influence of changes in sexual behaviour.英国男同性恋群体中1型人类免疫缺陷病毒的传播动力学:性行为变化的影响。
Philos Trans R Soc Lond B Biol Sci. 1989 Sep 5;325(1226):45-98. doi: 10.1098/rstb.1989.0074.
3
Human immunodeficiency virus infection in the United Kingdom: quarterly report I. The epidemic to 30 September 1987.
J Infect. 1988 May;16(3):291-302. doi: 10.1016/s0163-4453(88)97724-9.
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Projections of the HIV/AIDS epidemic for homosexual/bisexual men in France, the Federal Republic of Germany and the United Kingdom.
Eur J Epidemiol. 1990 Jun;6(2):124-35. doi: 10.1007/BF00145784.
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Sexual partner selectiveness effects on homosexual HIV transmission dynamics.
J Acquir Immune Defic Syndr (1988). 1988;1(5):486-504.
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Transmission dynamics of HIV infection.HIV感染的传播动力学
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The supply and demand dynamics of sexual behavior: implications for heterosexual HIV epidemics.性行为的供需动态:对异性传播艾滋病毒流行情况的影响
J Acquir Immune Defic Syndr (1988). 1991;4(10):987-99.
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AIDS: a challenge for the public health.艾滋病:对公共卫生的一项挑战。
Lancet. 1986 Mar 22;1(8482):662-6. doi: 10.1016/s0140-6736(86)91736-8.
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AIDS in sub-Saharan Africa: the epidemiology of heterosexual transmission and the prospects for prevention.撒哈拉以南非洲地区的艾滋病:异性传播流行病学及预防前景
Epidemiology. 1993 Jan;4(1):63-72.
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Heterosexually acquired HIV infection.异性传播获得性HIV感染
BMJ. 1989 Feb 18;298(6671):401-2. doi: 10.1136/bmj.298.6671.401.

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BMJ. 1988 Sep 17;297(6650):711-3. doi: 10.1136/bmj.297.6650.711.
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Estimation and projection of adult AIDS cases: a simple epidemiological model.成人艾滋病病例的估计与预测:一个简单的流行病学模型。
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