Neilson Laura J, Rutter Matthew D, Saunders Brian P, Plumb Andrew, Rees Colin J
Department of Gastroenterology, South Tyneside District Hospital, South Shields, UK.
Northern Region Endoscopy Group, Northern England, UK.
Frontline Gastroenterol. 2015 Apr;6(2):117-126. doi: 10.1136/flgastro-2015-100565. Epub 2015 Mar 6.
Colorectal cancer is the second most common cancer affecting men and women in England. The introduction of National Bowel Cancer Screening in 2006 has led to a rise in the proportion of colorectal cancers detected at an early stage. Many screen-detected cancers are malignant colorectal polyps and may potentially be cured with endoscopic resection, without recourse to the risk of major surgery or prolonged adjuvant therapies. Endoscopic decision making is crucial to select those early lesions that may be suitable for local endoscopic excision as well as identifying lesions for surgical resection, thus avoiding unnecessary surgical intervention in some and ensuring potentially curative surgery in others. This paper uses the current evidence base to provide a structured approach to the assessment of potentially malignant polyps and their management. http://group.bmj.com/products/journals/instructions-for-authors/licence-forms.
在英国,结直肠癌是影响男性和女性的第二大常见癌症。2006年全国肠癌筛查项目的引入,使得早期检测出的结直肠癌比例有所上升。许多通过筛查发现的癌症是恶性结直肠息肉,有可能通过内镜切除治愈,而无需承担大手术风险或长期辅助治疗。内镜决策对于选择那些可能适合局部内镜切除的早期病变以及识别需要手术切除的病变至关重要,从而避免一些不必要的手术干预,并确保另一些患者得到可能治愈性的手术。本文利用当前的证据基础,提供一种结构化方法来评估潜在恶性息肉及其管理。http://group.bmj.com/products/journals/instructions-for-authors/licence-forms。