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本文引用的文献

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Disseminated enteroinvasive aspergillosis in a critically ill patient without severe immunocompromise.一名无严重免疫功能低下的重症患者发生播散性肠侵袭性曲霉病。
J Surg Case Rep. 2013 Nov 4;2013(11):rjt091. doi: 10.1093/jscr/rjt091.
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European evidence-based Consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease.欧洲关于炎症性肠病机会性感染预防、诊断和管理的循证共识
J Crohns Colitis. 2009 Jun;3(2):47-91. doi: 10.1016/j.crohns.2009.02.010. Epub 2009 Apr 26.
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Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients.侵袭性曲霉病：免疫功能低下患者的流行病学、诊断与管理
Drugs. 2007;67(11):1567-601. doi: 10.2165/00003495-200767110-00004.
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Invasive aspergillosis localised to the colon presenting as toxic megacolon.侵袭性曲霉菌病局限于结肠，表现为中毒性巨结肠。
Eur J Haematol. 2007 Mar;78(3):270-3. doi: 10.1111/j.1600-0609.2006.00812.x.
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Primary invasive aspergillosis of the digestive tract: report of two cases and review of the literature.原发性消化道侵袭性曲霉病：两例报告并文献复习
Infection. 2006 Dec;34(6):333-8. doi: 10.1007/s15010-006-5660-0.
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Disseminated aspergillosis following infliximab therapy in an immunosuppressed patient with Crohn's disease and chronic hepatitis C: a case study and review of the literature.英夫利昔单抗治疗后，一名患有克罗恩病和慢性丙型肝炎的免疫抑制患者发生播散性曲霉病：病例报告及文献复习
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Small-bowel infarction from disseminated aspergillosis.播散性曲霉病导致的小肠梗死
Dis Colon Rectum. 2004 Sep;47(9):1515-8. doi: 10.1007/s10350-004-0625-9. Epub 2004 Jul 8.
8
Invasive aspergillosis in 2002: an update.2002年侵袭性曲霉病：最新进展
Eur J Clin Microbiol Infect Dis. 2002 Mar;21(3):161-72. doi: 10.1007/s10096-002-0699-z. Epub 2002 Mar 22.
9
Disseminated aspergillosis inciting intestinal ischaemia and obstruction.播散性曲霉病引发肠道缺血和梗阻。
Br J Radiol. 2001 Dec;74(888):1145-7. doi: 10.1259/bjr.74.888.741145.
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Small bowel infarction by Aspergillus.曲霉所致小肠梗死
Haematologica. 1997 Mar-Apr;82(2):182-3.

播散性曲霉病导致穿孔性结肠炎结肠切除术后肠道衰竭。

Disseminated aspergillosis causing intestinal failure following colectomy for perforated colitis.

作者信息

McElvanna Kevin, Loughrey Maurice B, Gillespie Scott, Gardiner Keith R

机构信息

Department of Colorectal Surgery & Intestinal Failure, Royal Victoria Hospital, Belfast, UK.

Department of Histopathology, Royal Victoria Hospital, Belfast Trust,Belfast, UK.

出版信息

Frontline Gastroenterol. 2016 Apr;7(2):110-113. doi: 10.1136/flgastro-2014-100463. Epub 2014 Jul 23.

DOI:10.1136/flgastro-2014-100463
PMID:28839844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5369472/
Abstract

Disseminated aspergillosis is a rare, invasive, opportunistic, fungal infection associated with a high mortality. We report a non-fatal case diagnosed following extensive enterectomy for intestinal infarction in a patient recovering from emergency abdominal colectomy for perforated ulcerative colitis. This resulted in intestinal failure necessitating life-long parenteral nutrition and prolonged antifungal therapy.

摘要

播散性曲霉病是一种罕见的、侵袭性的、机会性真菌感染，死亡率很高。我们报告了一例非致命病例，该病例是在一名因溃疡性结肠炎穿孔行急诊腹部结肠切除术后恢复过程中，因肠梗死接受广泛肠切除术后确诊的。这导致了肠衰竭，需要终身肠外营养和长期抗真菌治疗。