MUHC Reproductive Centre, Department of Obstetrics and Gynecology, 888 Boul de Maisonneuve E #200, Montreal, Quebec, H2L 4S8, Canada.
J Assist Reprod Genet. 2017 Nov;34(11):1567-1569. doi: 10.1007/s10815-017-1025-0. Epub 2017 Aug 24.
The majority of milk in industrialized countries is obtained from pregnant cows, which contains increased levels of estrogen and progesterone compared to non-pregnant cows. The aim of this study was to quantify the amount of hormones present in milk with different fat content because previous studies on humans have shown potential effects of increased milk consumption on serum and urine hormone levels as well as on sperm parameters. However, it is unclear whether consumption of milk at the currently recommended levels would lead to systemic effects.
Samples of cow's milk of varying fat concentrations (0, 1, 2, 3.25, 10, and 35%) were analyzed via competitive ELISA assays.
Progesterone concentrations were significantly correlated to increasing fat content of milk (r = 0.8251, p = 0.04).
Research on conditions in which additional progesterone may have an effect on human health should consider inclusion of limitation of milk intake and its effects. Further studies are needed to determine the concentration of progesterone in milk of different fat content in other regions and countries and to quantify the potential pathophysiologic role.
在工业化国家，大多数牛奶都来自怀孕的奶牛，与未怀孕的奶牛相比，其雌激素和孕激素水平升高。本研究的目的是定量检测不同脂肪含量的牛奶中的激素含量，因为之前的人体研究表明，增加牛奶的摄入量可能会对血清和尿液中的激素水平以及精子参数产生潜在影响。然而，目前尚不清楚在推荐的摄入量下，牛奶的摄入是否会导致全身效应。
通过竞争性 ELISA 检测分析不同脂肪浓度（0、1、2、3.25、10 和 35%）的牛奶样本。
孕激素浓度与牛奶的脂肪含量呈显著正相关（r=0.8251，p=0.04）。
在研究其他情况下孕激素可能对人类健康产生影响的研究中，应考虑限制牛奶的摄入量及其影响。需要进一步的研究来确定其他地区和国家不同脂肪含量的牛奶中的孕激素浓度，并定量评估其潜在的病理生理学作用。
