Wang Wenyi, Wang Binghe
Department of Chemistry and Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, Georgia 30303, USA.
Chem Commun (Camb). 2017 Sep 12;53(73):10124-10127. doi: 10.1039/c7cc05392d.
Sulfur dioxide (SO) is an endogenously produced gaseous molecule, and is emerging as a potential gasotransmitter. Herein, we describe the first series of esterase-sensitive prodrugs inspired by modified Julia olefination as SO donors.
二氧化硫（SO）是一种内源性产生的气体分子，正逐渐成为一种潜在的气体递质。在此，我们描述了首个受改良朱利亚烯烃化反应启发而设计的、作为SO供体的酯酶敏感前药系列。
