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Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.

作者信息

Kawalekar Omkar U, O' Connor Roddy S, Fraietta Joseph A, Guo Lili, McGettigan Shannon E, Posey Avery D, Patel Prachi R, Guedan Sonia, Scholler John, Keith Brian, Snyder Nathaniel W, Blair Ian A, Milone Michael C, June Carl H

出版信息

Immunity. 2016 Mar 15;44(3):712. doi: 10.1016/j.immuni.2016.02.023.

DOI:10.1016/j.immuni.2016.02.023
PMID:28843072
Abstract
摘要

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[2]
Current Advances and Challenges in CAR-T Therapy for Hematological and Solid Tumors.

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[3]
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Oncoimmunology. 2025-12

[4]
Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure.

Nat Cancer. 2025-5-20

[5]
Advances in CAR optimization strategies based on CD28.

Front Immunol. 2025-3-13

[6]
Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity.

Cell Rep Med. 2025-3-18

[7]
A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function.

Cancer Res Commun. 2025-3-1

[8]
Immune effector cell-associated hematotoxicity: mechanisms, clinical manifestations, and management strategies.

Haematologica. 2025-6-1

[9]
Effectors of the Future: Universal Chimeric Antigen Receptor.

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[10]
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