Haghgoo Roza, Mehran Majid, Afshari Elahe, Zadeh Hamide Farajian, Ahmadvand Motahare
Department of Pediatric Dentistry, School of Dentistry, Shahed University, Tehran, Iran.
Department of Pediatric Dentistry, School of Dentistry, Kermanshah University of Medical Science, Kermanshah, Iran.
J Int Soc Prev Community Dent. 2017 Jul-Aug;7(4):180-185. doi: 10.4103/jispcd.JISPCD_150_17. Epub 2017 Jul 31.
The aims of the present study were to determine and compare the effects of different concentrations of extract, 0.2% chlorhexidine (CHX), and penicillin on and .
The laboratory study was done, for a period of 8 weeks. Minimum inhibitory concentration (MIC) in the test tube, minimum bactericidal concentration (MBC) in a plate culture medium, and growth inhibition zone diameter methods were used to compare the antibacterial effects of 0.2% CHX, penicillin, and different concentrations of root extract. The data were analyzed by SPSS version 24 using ANOVA and -test analysis.
The results showed root extract had antibacterial effect, but significant differences were in MIC and MBC against and with penicillin and 0.2% CHX mouthwash. In addition, the mean growth inhibition zones of all the concentrations of the plant extract were less than that of the positive control group ( = 0.001). However, the difference in the maximum growth inhibition zone from that with the negative control group was significant. In addition, the antibacterial effect of the extract increased with an increase in its concentration. The extract exerted a greater antibacterial effect on than on . The plant polyphenols content is 3.7% which is equivalent to 29.93 g/ml.
The root extract of exhibited antibacterial effects on and , but this effect was less than those of CHX mouthwash and penicillin. The antibacterial effect increased with an increase in the concentration of the extract.
本研究的目的是确定并比较不同浓度的提取物、0.2%氯己定（CHX）和青霉素对[具体对象1]和[具体对象2]的影响。
进行了为期8周的实验室研究。采用试管中的最低抑菌浓度（MIC）、平板培养基中的最低杀菌浓度（MBC）以及生长抑制圈直径法来比较0.2% CHX、青霉素和不同浓度的[植物名称]根提取物的抗菌效果。使用SPSS 24版通过方差分析和[具体检验方法]分析对数据进行分析。
结果表明[植物名称]根提取物具有抗菌作用，但在针对[具体对象1]和[具体对象2]的MIC和MBC方面，与青霉素和0.2% CHX漱口水存在显著差异。此外，所有浓度的植物提取物的平均生长抑制圈均小于阳性对照组（P = 0.001）。然而，与阴性对照组相比，最大生长抑制圈的差异具有显著性。此外，提取物的抗菌效果随其浓度的增加而增强。提取物对[具体对象1]的抗菌作用比对[具体对象2]的更强。植物多酚含量为3.7%，相当于29.93微克/毫升。
[植物名称]根提取物对[具体对象1]和[具体对象2]具有抗菌作用，但这种作用小于CHX漱口水和青霉素。抗菌效果随提取物浓度的增加而增强。
