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从塞内加尔急性腹泻患者中分离出的肠致病性大肠杆菌和产肠毒素大肠杆菌的血清群及黏附素多样性。

Multiplicity of serogroups and adhesins in enteropathogenic and enterotoxigenic Escherichia coli isolated from acute diarrhea in Senegal.

作者信息

Darfeuille-Michaud A, Forestier C, Masseboeuf R, Rich C, M'Boup S, Joly B, Denis F

出版信息

J Clin Microbiol. 1987 Jun;25(6):1048-51. doi: 10.1128/jcm.25.6.1048-1051.1987.

Abstract

Escherichia coli strains were isolated from 228 children with diarrhea in Senegal from 1982 to 1984. Among these E. coli involved in cases of diarrhea, we found that 20.3% were enteropathogenic E. coli. Only 3.9% of the strains adhered to the brush borders of human intestinal enterocytes, and they belonged to different serotypes. All these adhesion-positive strains possessed genes encoding for the heat-stable enterotoxin, but their adhesive factors were different regarding serology with anti-colonization factor sera, hemagglutination patterns, electron microscopy structures, or major surface protein subunits.

摘要

1982年至1984年期间,从塞内加尔228名腹泻儿童中分离出大肠杆菌菌株。在这些引发腹泻的大肠杆菌中,我们发现20.3%是肠致病性大肠杆菌。只有3.9%的菌株黏附于人类肠道肠上皮细胞的刷状缘,且它们属于不同的血清型。所有这些黏附阳性菌株都拥有编码热稳定肠毒素的基因,但就与抗定植因子血清的血清学、血凝模式、电子显微镜结构或主要表面蛋白亚基而言,它们的黏附因子有所不同。

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