用于检测A型产气荚膜梭菌肠毒素的玻片乳胶凝集试验的开发与初步评估
Development and preliminary evaluation of a slide latex agglutination assay for detection of Clostridium perfringens type A enterotoxin.
作者信息
McClane B A, Snyder J T
出版信息
J Immunol Methods. 1987 Jun 26;100(1-2):131-6. doi: 10.1016/0022-1759(87)90181-5.
PMID:2885377
Abstract
A slide latex agglutination (SLA) assay was developed for rapid screening for Clostridium perfringens type A enterotoxin (CPE). SLA specifically detected CPE added to buffer or normal feces (sensitivity limit of 1 microgram CPE/g feces). Using clinical fecal samples from C. perfringens food poisoning cases, a strong correlation was shown between SLA results and results from other CPE assays and between SLA results and illness status.
摘要
开发了一种玻片乳胶凝集（SLA）试验，用于快速筛查A型产气荚膜梭菌肠毒素（CPE）。SLA能特异性检测添加到缓冲液或正常粪便中的CPE（检测灵敏度为1微克CPE/克粪便）。使用来自产气荚膜梭菌食物中毒病例的临床粪便样本，结果表明SLA结果与其他CPE检测结果之间以及SLA结果与疾病状态之间存在很强的相关性。
Zotero 插件