Best J M, Welch J M, Baker D A, Banatvala J E
Lancet. 1987 Jul 11;2(8550):88-90. doi: 10.1016/s0140-6736(87)92745-0.
The effects of the rubella epidemics in 1978 and 1986 among patients attending antenatal clinics at St Thomas' Hospital were compared. Although many pregnant women who had been exposed to rubella-like illnesses were investigated in both 1978 (269) and 1986 (160), the number of cases of maternal rubella was substantially lower in 1986 (1) than in 1978 (17). Rubella vaccination of 11-14-year-old girls was introduced in the United Kingdom in 1970, but 10% of our patients were susceptible and only 36% gave a definite history of vaccination. Despite the smaller number of maternal rubella cases, substantial resources were expended on assessing patients who had been exposed to or who presented with rubella-like illnesses. In 1978 an intensification of the selective rubella vaccination campaign was recommended, but experience in the 1986 epidemic supports the view that the programme should be augmented by vaccination of preschool children with a combined measles, mumps, and rubella vaccine, with a view to rubella eradication.
对1978年和1986年在圣托马斯医院产前诊所就诊的患者中发生的风疹流行情况进行了比较。尽管在1978年（269例）和1986年（160例）对许多接触过风疹样疾病的孕妇进行了调查，但1986年的母亲风疹病例数（1例）明显低于1978年（17例）。英国于1970年开始对11至14岁女孩进行风疹疫苗接种，但我们的患者中有10%易感，只有36%有明确的疫苗接种史。尽管母亲风疹病例数较少，但仍花费了大量资源来评估接触过或出现风疹样疾病的患者。1978年建议加强选择性风疹疫苗接种运动，但1986年疫情的经验支持这样一种观点，即该计划应通过为学龄前儿童接种麻疹、腮腺炎和风疹联合疫苗来扩大，以期根除风疹。
