Best J M, Banatvala J E, Morgan-Capner P, Miller E
Department of Virology, United Medical and Dental School, Guy's Hospital, London.
BMJ. 1989 Sep 23;299(6702):773-5. doi: 10.1136/bmj.299.6702.773.
Five cases of asymptomatic maternal reinfection with rubella are described that occurred in England and Wales during 1985-8 and resulted in intrauterine infection. The criteria for diagnosing reinfection are described. In four cases the rubella contact was with the woman's own children. Two women had therapeutic abortions, rubella virus being recovered from the products of conception, and three were delivered of infants with congenitally acquired disease. Though the risks associated with maternal reinfection with rubella are very small and being measured in a prospective study, it is hoped that the recently introduced augmented programme of rubella vaccination will reduce rubella in the community and therefore this small risk still further.
本文描述了1985年至1988年期间在英格兰和威尔士发生的5例无症状孕妇风疹再感染病例，这些病例导致了宫内感染。文中描述了诊断再感染的标准。在4例病例中，风疹接触源是该女性自己的孩子。两名女性进行了治疗性流产，从流产产物中分离出风疹病毒，另外三名女性分娩出患有先天性疾病的婴儿。尽管孕妇风疹再感染相关的风险非常小，并且正在进行前瞻性研究来评估，但希望最近推出的加强型风疹疫苗接种计划能够减少社区中的风疹病例，从而进一步降低这种小风险。
