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体力活动与自杀意念:系统评价和荟萃分析。

Physical activity and suicidal ideation: A systematic review and meta-analysis.

机构信息

KU Leuven - University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium; KU Leuven - University of Leuven, University Psychiatric Centre, Leuven-Kortenberg, Belgium.

Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.

出版信息

J Affect Disord. 2018 Jan 1;225:438-448. doi: 10.1016/j.jad.2017.08.070. Epub 2017 Aug 24.

DOI:10.1016/j.jad.2017.08.070
PMID:28858658
Abstract

BACKGROUND

A potential approach to suicide prevention that has not been closely examined, but which holds promise in terms of widespread dissemination without major side-effects, is physical activity (PA). This systematic review and meta-analysis set out to: (a) explore associations between PA and suicidal ideation (SI) levels, and (b) investigate the effect of PA interventions on SI.

METHODS

Major electronic databases were searched from inception up to 05/2017 to identify quantitative studies reporting an association between PA and SI. A quantitative correlates synthesis and random effects meta-analysis were conducted.

RESULTS

Fourteen of 21 studies in adults (67%) (n = 130,737), 7/14 (50%) in adolescents (n = 539,170) and 2/3 (67%) in older adults (n = 50,745) found a significant negative association between PA- and SI-levels. Pooled adjusted meta-analysis of 14 effect sizes over eight studies and 80,856 people found that those who were "active" versus those who were "inactive" were less likely to have SI (OR = 0.87, 95%CI = 0.76-0.98). Additionally, meeting PA guidelines conferred a significant protective effect against SI (OR = 0.91, 95%CI = 0.51-0.99, P = 0.03; N studies = 3, n people = 122,395), while not meeting guidelines was associated with increased SI (OR = 1.16, 95%CI = 1.09-1.24, P < 0.001; N = 4, n = 78,860). Data from the intervention studies (N = 3, n = 121) was mixed and limited.

LIMITATIONS

Our findings are based mainly on cross-sectional studies, while the majority of studies did not include a rigorous physical activity assessment.

CONCLUSIONS

The current study suggests that higher PA levels are associated with lower SI. However, the associations observed need to be confirmed in prospective observational studies and controlled trials.

摘要

背景

预防自杀的一种潜在方法尚未得到密切研究,但在广泛传播方面具有很大的希望,且没有重大副作用,即身体活动(PA)。本系统综述和荟萃分析旨在:(a)探索身体活动与自杀意念(SI)水平之间的关联,以及(b)调查身体活动干预对 SI 的影响。

方法

从创建到 2017 年 5 月,主要电子数据库被搜索,以确定报告身体活动与 SI 之间关联的定量研究。进行了定量相关综合和随机效应荟萃分析。

结果

在成年人中,21 项研究中有 14 项(67%)(n = 130737),青少年中有 7/14 项(50%)(n = 539170)和老年人中有 2/3 项(67%)(n = 50745)发现身体活动水平与 SI 水平之间存在显著负相关。对 8 项研究中的 14 个效应量进行的汇总调整荟萃分析发现,与不活动相比,那些“活跃”的人不太可能出现 SI(OR = 0.87,95%CI = 0.76-0.98)。此外,符合身体活动指南显著降低了 SI 的保护作用(OR = 0.91,95%CI = 0.51-0.99,P = 0.03;N 项研究= 3,n 人= 122395),而不符合指南则与 SI 增加相关(OR = 1.16,95%CI = 1.09-1.24,P < 0.001;N = 4,n = 78860)。来自干预研究的数据(N = 3,n = 121)混杂且有限。

局限性

我们的研究结果主要基于横断面研究,而大多数研究未包括严格的身体活动评估。

结论

本研究表明,较高的身体活动水平与较低的 SI 水平相关。然而,需要在前瞻性观察研究和对照试验中确认观察到的关联。

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