Raffaeli William, Arnaudo Elisa
Fondazione ISAL Institute for Research on Pain, Torre Pedrera, Rimini, Italy.
J Pain Res. 2017 Aug 21;10:2003-2008. doi: 10.2147/JPR.S138864. eCollection 2017.
The acknowledgment of pain as a pathologic entity in its own right remains debated. Notwithstanding the data showing the burden of pain as a disease, an ultimate recognition of the pathologic nature of this condition is lacking. In this study, we analyze the notion of pain as a disease through an historical overview of its several conceptualizations and report the main evidence supporting this notion. We believe that a clear definition of pain as a disease is necessary, especially considering the enormous global burden of this condition. Indeed, the recognition of pain as a definite pathologic state is crucial to raise awareness about this neglected global health problem and to promote the exploration of new specific therapeutic approaches.
疼痛本身作为一种病理实体的认知仍存在争议。尽管有数据表明疼痛作为一种疾病的负担，但对于这种状况的病理性质仍缺乏最终的认可。在本研究中，我们通过对疼痛的几种概念化的历史概述来分析疼痛作为一种疾病的概念，并报告支持这一概念的主要证据。我们认为，将疼痛明确界定为一种疾病是必要的，尤其是考虑到这种状况在全球造成的巨大负担。事实上，将疼痛确认为一种明确的病理状态对于提高对这一被忽视的全球健康问题的认识以及促进探索新的特定治疗方法至关重要。
