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先天性双行睫:3例组织病理学报告。

Congenital distichiasis: Histopathological report of 3 cases.

作者信息

Alkatan Hind Manaa, Galindo-Ferreiro Alicia, Maktabi Azza, Galvez-Ruiz Alberto, Schellini Silvana

机构信息

Departments of Ophthalmology & Pathology, King Saud University College of Medicine, Riyadh, Saudi Arabia.

Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia.

出版信息

Saudi J Ophthalmol. 2017 Jul-Sep;31(3):165-168. doi: 10.1016/j.sjopt.2017.05.003. Epub 2017 May 18.

DOI:10.1016/j.sjopt.2017.05.003
PMID:28860915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5569325/
Abstract

Distichiasis is a condition clinically presenting as partial or complete accessory row of lashes that emerges from the meibomian glands orifices. It can be an acquired or congenital with an autosomal dominant inheritance. The histopathological features are not well described in the ophthalmic literature, however they include abnormal pilosebaceous units within the posterior lamella of the eyelid and perifollicular chronic inflammatory cell infiltration. In this report, we describe the histopathological findings of three congenital distichiasis cases treated at King Khaled Eye Specialist Hospital (KKESH), Riyadh, Saudi Arabia with discussion on the pathogenesis of such a condition and the differentiating features from ectopic cilia.

摘要

双行睫是一种临床上表现为从睑板腺开口处出现部分或完整副睫毛排的病症。它可以是后天获得性的,也可以是常染色体显性遗传的先天性疾病。眼科文献中对其组织病理学特征描述不多,不过这些特征包括眼睑后层内异常的皮脂腺单位以及毛囊周围慢性炎性细胞浸润。在本报告中,我们描述了沙特阿拉伯利雅得国王哈立德眼科专科医院治疗的3例先天性双行睫病例的组织病理学发现,并讨论了该病症的发病机制以及与异位睫的鉴别特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e08b/5569325/4f35e771fd65/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e08b/5569325/c68c0a556650/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e08b/5569325/4f35e771fd65/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e08b/5569325/c68c0a556650/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e08b/5569325/4f35e771fd65/gr2.jpg

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1
Congenital distichiasis: Histopathological report of 3 cases.先天性双行睫:3例组织病理学报告。
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2
Lid splitting and posterior lamella cryosurgery for congenital and acquired distichiasis.睑裂劈开及后层冷冻手术治疗先天性和后天性双行睫
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Excision of individual follicles for the management of congenital distichiasis and localized trichiasis.切除单个毛囊以治疗先天性双行睫和局限性倒睫。
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引用本文的文献

1
Distichiasis: An update on etiology, treatment and outcomes.倒睫:病因、治疗和结局的最新进展。
Indian J Ophthalmol. 2022 Apr;70(4):1100-1106. doi: 10.4103/ijo.IJO_1141_21.
2
Congenital Eyelid Anomalies: What General Physicians Need To Know.先天性眼睑异常:普通内科医生需要了解的内容。
Oman Med J. 2021 Jul 6;36(4):e279. doi: 10.5001/omj.2021.26. eCollection 2021 Jul.
3
A Rare Case Report of Posterior Ectopic Cilia in a 41-Year-Old Saudi Male.一名41岁沙特男性后位异位纤毛的罕见病例报告。

本文引用的文献

1
Histopathologic proof for the origin of ectopic cilia of the eyelid skin.组织病理学证明了眼睑皮肤异位睫毛的起源。
Graefes Arch Clin Exp Ophthalmol. 2013 Mar;251(3):985-8. doi: 10.1007/s00417-012-2224-0. Epub 2012 Dec 22.
2
Ectopic cilia: a histopathological study.异位纤毛:一项组织病理学研究。
Case Rep Dermatol. 2012 Jan;4(1):37-40. doi: 10.1159/000336887. Epub 2012 Feb 10.
3
Histopathologic features of canine distichiasis.犬双行睫的组织病理学特征。
Case Rep Ophthalmol. 2020 Nov 23;11(3):626-629. doi: 10.1159/000510130. eCollection 2020 Sep-Dec.
4
Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses.全基因组测序鉴定出弗里西亚马的 ECA13 上与双行睫毛有关的 16 千碱基缺失。
BMC Genomics. 2020 Nov 30;21(1):848. doi: 10.1186/s12864-020-07265-8.
Vet Ophthalmol. 2012 Mar;15(2):92-7. doi: 10.1111/j.1463-5224.2011.00946.x. Epub 2011 Sep 29.
4
Distichiasis.双行睫
Am J Ophthalmol. 1962 Jan;53:14-8. doi: 10.1016/0002-9394(62)90387-2.
5
Distichiasis: management with cryotherapy to the posterior lamella.双行睫:对后板层进行冷冻治疗的处理方法。
Br J Ophthalmol. 1993 May;77(5):289-92. doi: 10.1136/bjo.77.5.289.
6
Lid splitting and posterior lamella cryosurgery for congenital and acquired distichiasis.睑裂劈开及后层冷冻手术治疗先天性和后天性双行睫
Arch Ophthalmol. 1981 Apr;99(4):631-4. doi: 10.1001/archopht.1981.03930010631008.
7
Distichiasis and trichiasis: origin and management.双行睫和倒睫:病因及治疗
Am J Ophthalmol. 1966 Apr;61(4):718-20. doi: 10.1016/0002-9394(66)91209-8.
8
Distichiasis and lymphedema: a hereditary syndrome with possible multiple defects. A report of a family.双行睫与淋巴水肿:一种可能存在多种缺陷的遗传性综合征。一家系报告。
Trans Am Ophthalmol Soc. 1971;69:293-306.
9
Excision of individual follicles for the management of congenital distichiasis and localized trichiasis.切除单个毛囊以治疗先天性双行睫和局限性倒睫。
J Pediatr Ophthalmol Strabismus. 1987 Jan-Feb;24(1):22-6. doi: 10.3928/0191-3913-19870101-06.
10
Correction of distichiasis by tarsal resection and mucous membrane grafting.睑板切除联合黏膜移植治疗双行睫
Am J Ophthalmol. 1975 Sep;80(3 Pt 2):507-8. doi: 10.1016/0002-9394(75)90216-0.