The Johnson Center for Child Health and Development, 1700 Rio Grande Street, Austin, TX, 78701, USA.
Care Improvement Plus Practitioners, XLHealth, Utah, Pleasant Grove, USA.
J Autism Dev Disord. 2017 Nov;47(11):3608-3619. doi: 10.1007/s10803-017-3277-z.
This study compared bone mineral density (BMD) of the spine obtained by dual-energy X-ray absorptiometry (DEXA), nutritional status, biochemical markers, and gastrointestinal (GI) symptoms in 4-8 year old boys with Autism Spectrum Disorder (ASD) with a group of age-matched, healthy boys without ASD. Boys with ASD had significantly lower spine BMD compared to controls but this was not correlated with any biochemical markers, dietary intake of calcium and vitamin D, elimination diet status, or GI symptomology. Reduced BMD in 4-8 year old boys with ASD appears to involve factors other than nutrient intake and GI status, and requires further study.
本研究比较了 4-8 岁自闭症谱系障碍(ASD)男孩和年龄匹配的健康男孩的骨密度(BMD)、营养状况、生化标志物和胃肠道(GI)症状。与对照组相比,ASD 男孩的脊柱 BMD 显著降低,但这与任何生化标志物、钙和维生素 D 的饮食摄入量、消除饮食状态或 GI 症状均无相关性。4-8 岁 ASD 男孩的低骨密度似乎涉及营养摄入和 GI 状况以外的因素,需要进一步研究。