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[心得安对实验性口腔炎犬口腔黏膜酪氨酸羟化酶活性的影响]

[Effect of anaprilin on the tyrosine hydroxylase activity of the oral mucosa in dogs with experimental stomatitis].

作者信息

Aĭrapetian G O, Kudrin V S

出版信息

Farmakol Toksikol. 1987 May-Jun;50(3):106-9.

PMID:2886361
Abstract

It was shown that in dogs with experimental aphthous stomatitis (ligation of the common bile duct) tyrosine hydroxylase activity and content of catecholamines (CA) in the oral mucosa were increased. Blockade of beta-adrenoreceptors caused by anaprilin (1 mg/kg) led to the further increase of tyrosine hydroxylase activity. A relative decrease of CA content was simultaneously observed.

摘要

结果表明,在患有实验性口疮性口炎(胆总管结扎)的犬中,口腔黏膜中酪氨酸羟化酶活性和儿茶酚胺(CA)含量增加。心得安(1毫克/千克)引起的β-肾上腺素能受体阻断导致酪氨酸羟化酶活性进一步增加。同时观察到CA含量相对下降。

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