Early Psychosis Intervention Center Region Zealand, University Hospital Copenhagen, Smedegade 10, 4000, Roskilde, Denmark.
Mental Health Center Glostrup, University Hospital Copenhagen, Broendbyoestervej 160, 2605, Broendy, Denmark.
Eur Arch Psychiatry Clin Neurosci. 2018 Oct;268(7):713-718. doi: 10.1007/s00406-017-0837-3. Epub 2017 Sep 1.
Self-disorders have been hypothesized to be an underlying and trait-like core feature of schizophrenia-spectrum disorders and a certain degree of temporal stability of self-disorders would therefore be expected. The aim of the study was to examine the persistence of self-disorders measured by the Examination of Anomalous Self Experiences over a time span of 5 years. 48 patients with schizophrenia-spectrum disorders were thoroughly assessed for psychopathology at baseline and 5 years later. Self-disorders were assessed by the Examination of Anomalous Self Experiences. The level of self-disorders was same at the two occasions for the full Examination of Anomalous Self Disorders and for four out of the five domains. For one domain, the level of self-disorders increased slightly from baseline to follow-up. The correlations between baseline and follow-up were moderate. 9 out of the 13 most-frequently rated items at baseline showed equal frequencies at follow-up. The baseline level of self-disorders predicted global symptomatic, but not functional outcome. Self-disorders measured by the Examination of Anomalous Self Experiences show a high level of temporal persistence over 5 years and predict symptomatic outcome.
自我障碍被假设为精神分裂症谱系障碍的潜在和特质样核心特征，因此预计自我障碍会有一定程度的时间稳定性。本研究的目的是在 5 年的时间跨度内，通过异常自我体验检查来检验自我障碍的持续性。48 名精神分裂症谱系障碍患者在基线和 5 年后接受了全面的精神病学评估。自我障碍通过异常自我体验检查进行评估。在两次检查中，完整的异常自我障碍检查和五个领域中的四个领域的自我障碍水平相同。对于一个领域，自我障碍的水平从基线到随访略有增加。基线和随访之间的相关性是中等的。在基线时被评为最常见的 13 个项目中的 9 个在随访时的频率相同。自我障碍的基线水平预测了总体症状，但不能预测功能结果。通过异常自我体验检查测量的自我障碍在 5 年内具有高度的时间持续性，并预测症状结果。
