Thibaut Florence
University Hospital Cochin (Site Tarnier), Faculty of Medicine Paris Descartes, INSERM U 894, CNP, Paris, France.
Dialogues Clin Neurosci. 2017 Jun;19(2):87-88. doi: 10.31887/DCNS.2017.19.2/fthibaut.
Anxiety disorders are the most prevalent psychiatric disorders. There is a high comorbidity between anxiety (especially generalized anxiety disorders or panic disorders) and depressive disorders or between anxiety disorders, which renders treatment more complex. Current guidelines do not recommend benzodiazepines as first-line treatments due to their potential side effects. Selective serotonin reuptake inhibitors and selective serotonin norepinephrine reuptake inhibitors are recommended as first-line treatments. Psychotherapy, in association with pharmacotherapy, is associated with better efficacy. Finally, a bio-psycho-social model is hypothesized in anxiety disorders.
焦虑症是最常见的精神疾病。焦虑症(尤其是广泛性焦虑症或惊恐障碍)与抑郁症之间或焦虑症之间存在高度共病现象,这使得治疗更加复杂。由于苯二氮䓬类药物存在潜在副作用,目前的指南不推荐将其作为一线治疗药物。选择性5-羟色胺再摄取抑制剂和选择性5-羟色胺去甲肾上腺素再摄取抑制剂被推荐为一线治疗药物。心理治疗与药物治疗相结合,疗效更佳。最后,针对焦虑症提出了一种生物-心理-社会模型。