Kharkevich D D
Biull Eksp Biol Med. 1987 Jul;104(7):69-71.
With the help of spontaneous lymphocyte adhesion test it was demonstrated that acetylcholine and carbacholine enhanced the adhesion of lymphocytes. The enhancement revealed was completely abolished by a specific M-cholinergic blocker--atropine, but not N-cholinergic blocker--hexonium. Thus, the enhancement of spontaneous human lymphocyte adhesion by cholinergic stimulation is mediated by M-cholinoreceptors. It is suggested that the phenomenon revealed is mediated by the enhancement of cGMP intracellular levels after cholinergic stimulation.
借助自发淋巴细胞黏附试验表明，乙酰胆碱和卡巴胆碱可增强淋巴细胞的黏附。所发现的这种增强作用被特异性M胆碱能阻滞剂——阿托品完全消除，但未被N胆碱能阻滞剂——己烷双铵消除。因此，胆碱能刺激对人自发淋巴细胞黏附的增强作用是由M胆碱受体介导的。有人提出，所发现的这一现象是由胆碱能刺激后细胞内cGMP水平升高介导的。
