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印度传统医学姜黄素治疗人类疾病的生物学潜力

The Biological Potentialsof Indian Traditional Medicine, Curcumin for Treating Human Diseases.

作者信息

Sumathi C S, Rajesh P, Kannan V. Rajesh

机构信息

Department of Microbiology, K.S.Rangasamy College of Arts and Science, Tiruchengode 637215. India.

Department of Microbiology, Bharathidasan University, Tiruchirappalli 620 024, TamilNadu, India

出版信息

Cardiovasc Hematol Agents Med Chem. 2017 Aug 30. doi: 10.2174/1871525715666170830130555.

Abstract

Curcumin is an active compound extracted from the rhizomes of Curcuma longa L. (Turmeric). It possesses a di phenolic structure and there are three important fractions of curcumin namely curcumin, mono-desmethoxycurcumin and bis-desmethoxycurcumin. Curcumin is having high medicinal value. It is widely in Ayurveda, Siddha and Unani medicine formulations to treat various diseases. It is effective against microbial pathogens like bacteria, virus and fungi. It is highly potent and kills cancerous cells. Curcumin exhibits antioxidant activity and reduces lipoperoxidation. Cardioprotective nature of curcumin is also reported. It can protect the brain from neurodegenerative disorders caused by oxidative stress. It is safe to use in humans and animals. In addition to its medicinal value, it is also having numerous commercial applications like dyeing, cooking purposes and antiseptics etc. The cultivation of turmeric by means of inorganic inputs makes it contaminated with heavy metals is reported. Improving the biological use of curcumin provides healthy humankind and increases the economic status of a country.

摘要

姜黄素是从姜黄属植物姜黄(Curcuma longa L.)的根茎中提取的一种活性化合物。它具有二酚结构,姜黄素有三个重要组分,即姜黄素、单去甲氧基姜黄素和双去甲氧基姜黄素。姜黄素具有很高的药用价值。它广泛用于阿育吠陀医学、悉达医学和尤那尼医学配方中,以治疗各种疾病。它对细菌、病毒和真菌等微生物病原体有效。它具有高效性,能杀死癌细胞。姜黄素具有抗氧化活性,可减少脂质过氧化。姜黄素的心脏保护作用也有报道。它可以保护大脑免受氧化应激引起的神经退行性疾病的影响。它在人类和动物中使用是安全的。除了其药用价值外,它还具有许多商业应用,如染色、烹饪用途和防腐剂等。据报道,通过无机投入物种植姜黄会使其受到重金属污染。提高姜黄素的生物利用度可为人类健康做出贡献,并提高一个国家的经济水平。

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