Daniels R
Pharmazeutische Technologie, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Deutschland.
Hautarzt. 2017 Nov;68(11):912-915. doi: 10.1007/s00105-017-4044-y.
It is international consensus that the daily use of properly selected products for the maintenance therapy is a must in the adjuvant treatment of most chronic skin diseases. In a first step, the selection of an adequate product can be guided by the classical triangle of the dermal vehicles. However, modern skin care products use diverse excipients, e. g. emulsifiers and viscosity enhancers, to improve the galenical and haptic properties of the formulations. It is thus no longer sufficient to simply have knowledge about the oil and water content of a cream in order to make a proper selection. A very positive effect on the skin barrier can be achieved using biomimetic lipids which can be incorporated into the epidermal lipid barrier. The application of such products as a foam cream is the most convenient way especially favorable when inflamed or hardly accessible skin areas have to be treated.
国际共识认为，在大多数慢性皮肤病的辅助治疗中，每日使用经过适当选择的产品进行维持治疗是必不可少的。第一步，合适产品的选择可以由皮肤载体的经典三角来指导。然而，现代护肤品使用多种辅料，例如乳化剂和增稠剂，来改善制剂的药剂学和触觉特性。因此，仅仅了解乳膏的油和水含量已不足以做出恰当的选择。使用可融入表皮脂质屏障的仿生脂质，对皮肤屏障可产生非常积极的效果。将此类产品制成泡沫乳膏应用是最方便的方式，在必须治疗发炎或难以触及的皮肤区域时尤其有利。
