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[皮肤科的基础或维持治疗。合适的剂型、可能性及局限性]

[Basic or maintenance therapy in dermatology. Appropriate vehicles, possibilities and limitations].

作者信息

Staubach P, Lunter D J

机构信息

Hautklinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland,

出版信息

Hautarzt. 2014 Jan;65(1):63-72; quiz 73-4. doi: 10.1007/s00105-013-2726-7.

DOI:10.1007/s00105-013-2726-7
PMID:24445946
Abstract

Topical therapy of dermatological diseases includes treatment with active ingredients in combination with basic or maintenance therapy. An appropriate basic therapy can be used as prophylaxis to avoid or decrease occurrence of disease episodes and therefore counteract chronic disease manifestations. Long-term basic therapy is suitable especially for chronic dermatoses to prevent the onset of symptoms. This also makes basic therapy a type of preventive therapy. At the same time, adequate basic therapy leads to an increased quality of life, which is often considerably reduced in patients with a chronic dermatologic disease. Choosing the right vehicle for basic therapy is an important criterion along with the choice of appropriate active ingredients for successful treatment. This should be done using established standard vehicles recommended in the various pharmacopeia.

摘要

皮肤病的局部治疗包括使用活性成分进行治疗,并结合基础治疗或维持治疗。适当的基础治疗可作为预防措施,以避免或减少疾病发作的发生,从而对抗慢性疾病表现。长期基础治疗特别适用于慢性皮肤病,以预防症状的出现。这也使基础治疗成为一种预防性治疗。同时,适当的基础治疗可提高生活质量,而慢性皮肤病患者的生活质量往往会大幅下降。选择合适的基础治疗载体是成功治疗的一个重要标准,与选择合适的活性成分一样重要。这应使用各种药典中推荐的既定标准载体来进行。

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Magistral formulations and pruritus therapy - What is established, what is confirmed, what is new?药剂学配方与瘙痒症治疗——哪些已确立,哪些已证实,哪些是新进展?
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[Individualized drug compounding].
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[Basic therapeutics : What are the features of modern personal care products to protect and regenerate the skin barrier?].[基础治疗学:现代个人护理产品保护和修复皮肤屏障的特点有哪些?]
Hautarzt. 2017 Nov;68(11):912-915. doi: 10.1007/s00105-017-4044-y.
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Hautarzt. 2016 Oct;67(10):833-844. doi: 10.1007/s00105-016-3868-1.
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[Extemporaneous magistral formulas for the topical treatment of pruritus : Proven and new options].[用于局部治疗瘙痒症的临时调配经验方:已证实的及新的选择]
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Topical treatments for scalp psoriasis.头皮银屑病的局部治疗
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Multicentre study 'rehabilitation of occupational skin diseases -optimization and quality assurance of inpatient management (ROQ)'-results from 12-month follow-up.多中心研究“职业性皮肤病的康复——住院管理的优化和质量保证 (ROQ)——12 个月随访结果。”
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Hautarzt. 2012 Aug;63(8):606-7. doi: 10.1007/s00105-012-2426-8.
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Guidelines for treatment of atopic eczema (atopic dermatitis) Part II.特应性皮炎(特应性湿疹)治疗指南(二)。
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J Eur Acad Dermatol Venereol. 2012 Aug;26(8):1045-60. doi: 10.1111/j.1468-3083.2012.04635.x.
8
Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression.尿素摄取通过调节表皮基因表达增强人体的屏障功能和抗菌防御。
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Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study.甘油和石蜡联合治疗儿童鱼鳞病:一项国际性、多中心、随机、对照、双盲研究。
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