Gandhi Kapil, Datta Geetika, Ahuja Shilpa, Saxena Tanvi, G Datta Ankush
Professor, Department of Pedodontics and Preventive Dentistry Inderprastha Dental College & Hospital, Ghaziabad, Uttar Pradesh, India.
Reader, Department of Pedodontics and Preventive Dentistry Inderprastha Dental College & Hospital, Ghaziabad, Uttar Pradesh, India.
Int J Clin Pediatr Dent. 2017 Apr-Jun;10(2):166-171. doi: 10.5005/iD-iournals-10005-1428. Epub 2017 Jun 1.
Multiagent chemotherapy, radiotherapy, or a combination of both are the contemporary methods of cancer treatment. With medical advancements, though cure rates have increased considerably, focus is now shifted to the potential early and late complications of the same. The aim of this study was to assess the early oral complications in pediatric patients receiving chemotherapy. Sixty-two children with cancer undergoing chemotherapy with the mean age of 7.42 ± 3.6 years were included in the study. The various types of malignancies and oral problems during chemotherapy were recorded in the subjects. The most commonly encountered malignancy was acute lymphoblastic leukemia at 35.5%. Various oral and associated complications like mucosal inflammation with ulcerations, oral pain, xerostomia, and secondary infections were commonly seen, with mucositis being the most commonly observed complication in 58.1% of the subjects undergoing chemotherapy. Clinical importance of timely medical and dental interventions by a multidisciplinary team involving a pediatric dentist at different stages of anticancer treatment is also emphasized to minimize discomfort, increase treatment compliance, and improve the quality of life of pediatric patients.
Gandhi K, Datta G, Ahuja S, Saxena T, Datta AG. Prevalence of Oral Complications occurring in a Population of Pediatric Cancer Patients receiving Chemotherapy. Int Int J Clin Pediatr Dent 2017;10(2):166-171.
多药化疗、放疗或两者联合是当代癌症治疗方法。随着医学进步，尽管治愈率有了显著提高，但现在重点已转向这些治疗方法潜在的早期和晚期并发症。本研究的目的是评估接受化疗的儿科患者的早期口腔并发症。本研究纳入了62例正在接受化疗的癌症患儿，平均年龄为7.42±3.6岁。记录了受试者化疗期间的各种恶性肿瘤类型和口腔问题。最常见的恶性肿瘤是急性淋巴细胞白血病，占35.5%。常见各种口腔及相关并发症，如伴有溃疡的黏膜炎症、口腔疼痛、口干和继发感染，其中黏膜炎是58.1%接受化疗的受试者中最常见的并发症。还强调了由包括儿科牙医在内的多学科团队在抗癌治疗的不同阶段及时进行医学和牙科干预的临床重要性，以尽量减少不适、提高治疗依从性并改善儿科患者的生活质量。
甘地·K、达塔·G、阿胡贾·S、萨克森纳·T、达塔·AG。接受化疗的儿科癌症患者群体中口腔并发症的患病率。《国际临床儿科牙科杂志》2017年；10(2)：166 - 171。
