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Endocuff辅助结肠镜检查显著提高了退伍军人中无蒂锯齿状腺瘤的检出率。

Endocuff assisted colonoscopy significantly increases sessile serrated adenoma detection in veterans.

作者信息

Baek Michael D, Jackson Christian S, Lunn John, Nguyen Chris, Shah Nicole K, Serrao Steve, Juma David, Strong Richard M

机构信息

Loma Linda University Medical Center, Loma Linda, CA, USA.

Loma Linda VA Medical Center, Loma Linda, CA, USA.

出版信息

J Gastrointest Oncol. 2017 Aug;8(4):636-642. doi: 10.21037/jgo.2017.03.07.

Abstract

BACKGROUND

Colorectal cancer (CRC) is the second most common cause of cancer related deaths in the United States. Colonoscopy is the gold standard for the detection of CRC. There are many colonoscopy quality measures and among these the adenoma detection rate (ADR) has demonstrated a significant impact in reducing mortality from CRC. The primary aim of our study was to compare ADR and distribution of polyp type in patients undergoing Endocuff-assisted colonoscopy (EAC) versus standard colonoscopy (SC) in a VA system.

METHODS

Retrospective data was collected from 496 patients who underwent routine screening, surveillance and diagnostic colonoscopies either via SC from January 6, 2014 through March 12, 2014 or EAC from September 24, 2014 through February 19, 2015. A total of 54 patients were excluded based on a personal history of CRC and prior resection, incomplete colonoscopy due to poor bowel preparation, and removal or loss of Endocuff (EC). Primary outcomes measured and compared were ADR and types of polyps found.

RESULTS

The overall ADR in the EAC group was higher at 59.91% versus 50.66% for SC, accounting for a 9% increase (P=0.0508). EAC was able to detect a total of 59 sessile serrated adenoma/polyps (SSA/Ps) compared to SC only detecting 8 (P≤0.0001). There was a significant increase in the SSA/P detection rate with EAC at 15% versus 3% in the SC group (P≤0.0001).

CONCLUSIONS

EAC significantly increases the detection of SSA/P and has shown a trend in improving ADR in our veteran population.

摘要

背景

在美国,结直肠癌(CRC)是癌症相关死亡的第二大常见原因。结肠镜检查是检测CRC的金标准。有许多结肠镜检查质量指标,其中腺瘤检出率(ADR)已证明对降低CRC死亡率有显著影响。我们研究的主要目的是比较退伍军人事务部(VA)系统中接受Endocuff辅助结肠镜检查(EAC)与标准结肠镜检查(SC)的患者的ADR和息肉类型分布。

方法

收集了496例患者的回顾性数据,这些患者在2014年1月6日至2014年3月12日期间接受了SC常规筛查、监测和诊断性结肠镜检查,或在2014年9月24日至2015年2月19日期间接受了EAC检查。基于CRC个人病史和先前切除史、因肠道准备不佳导致结肠镜检查不完整以及Endocuff(EC)移除或丢失,共排除54例患者。测量和比较的主要结局是ADR和发现的息肉类型。

结果

EAC组的总体ADR较高,为59.91%,而SC组为50.66%,增加了9%(P = 0.0508)。与SC仅检测到8例相比,EAC能够检测到总共59例无蒂锯齿状腺瘤/息肉(SSA/P)(P≤0.0001)。EAC的SSA/P检出率显著增加,为15%,而SC组为3%(P≤0.0001)。

结论

EAC显著增加了SSA/P的检出率,并在我们的退伍军人人群中显示出改善ADR的趋势。

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