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在一项有组织的筛查项目中,Endocuff辅助结肠镜检查对腺瘤检测的影响。

The impact of Endocuff-assisted colonoscopy on adenoma detection in an organized screening program.

作者信息

Cavallaro Lucas G, Hassan Cesare, Lecis Pierenrico, Galliani Ermenegildo, Dal Pont Elisabetta, Iuzzolino Paolo, Roldo Claudia, Soppelsa Fabio, Germanà Bastianello

机构信息

Gastroenterology Unit, San Martino Hospital, ULSS 1, Belluno, Italy.

Gastroenterology Unit, Nuovo Regina Margherita Hospital, Rome Italy.

出版信息

Endosc Int Open. 2018 Apr;6(4):E437-E442. doi: 10.1055/a-0578-8515. Epub 2018 Mar 29.

Abstract

BACKGROUND AND STUDY AIMS

Colorectal cancer (CRC) screening with biennial fecal occult blood test has been shown to reduce CRC mortality. For the effectiveness of the CRC screening program is crucial that a high-quality colonoscopy with a high adenoma detection rate (ADR) be performed. To improve ADR, various endoscopic devices have been developed. Endocuff, an endoscopic cap with finger-like projections, has been shown to improve ADR. The aim of this study was to compare in an organized CRC screening program ADR, advanced adenoma detection rate (AADR) and mean number of adenomas per patient (MAP) using standard colonoscopy (SC) and Endocuff-assisted colonoscopy (EAC).

PATIENTS AND METHODS

We compared performance of SC (in 2014) and EAC (in 2015) in consecutive participants in an organized CRC screening program.

RESULTS

SC and EAC were performed in 546 (284 males) and 519 (293 males) subjects, respectively (mean age 60 years). Cecal intubation rate was 97.4 % for SC and 97.1 % for EAC and not significantly different (  = 0.7). ADR was 47 % for SC and 52 % for EAC,  = 0.1. MAP in SC and EAC were 0.87 (range: 0 - 7) and 1.11 (range: 0 - 13) respectively,  = 0.02. AADR rate was 25 % and 23 % for SC and EAC, respectively,  = 0.5.

CONCLUSION

Endocuff-assisted colonoscopy does not improve the number of patients with at least one adenoma but it may increase the number of detected adenomas per procedure.

摘要

背景与研究目的

每两年进行一次粪便潜血检测的结直肠癌(CRC)筛查已被证明可降低结直肠癌死亡率。高质量的结肠镜检查及高腺瘤检出率(ADR)对于CRC筛查项目的有效性至关重要。为提高ADR,已研发出多种内镜设备。Endocuff是一种带有指状突起的内镜帽,已被证明可提高ADR。本研究的目的是在有组织的CRC筛查项目中,比较使用标准结肠镜检查(SC)和Endocuff辅助结肠镜检查(EAC)时的ADR、高级别腺瘤检出率(AADR)以及每位患者的腺瘤平均数量(MAP)。

患者与方法

我们比较了有组织的CRC筛查项目中连续参与者在2014年的SC和2015年的EAC的表现。

结果

分别对546名(284名男性)和519名(293名男性)受试者进行了SC和EAC(平均年龄60岁)。SC的盲肠插管率为97.4%,EAC为97.1%,差异无统计学意义(P = 0.7)。SC的ADR为47%,EAC为52%,P = 0.1。SC和EAC的MAP分别为0.87(范围:0 - 7)和1.11(范围:0 - 13),P = 0.02。SC和EAC的AADR率分别为25%和23%,P = 0.5。

结论

Endocuff辅助结肠镜检查不会增加至少有一个腺瘤的患者数量,但可能会增加每次检查中检测到的腺瘤数量。

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