Geirsdottir O G, Chang M, Briem K, Jonsson P V, Thorsdottir I, Ramel A
The Icelandic Gerontological Research Center, Reykjavik, Iceland.
Faculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland.
J Aging Res. 2017;2017:5841083. doi: 10.1155/2017/5841083. Epub 2017 Aug 14.
Resistance exercise training can be effective against sarcopenia. We identified predictors of drop-out and compared physical outcomes between men and women after such training.
Subjects ( = 236, 73.7 ± 5.7 years) participated in a 12-week resistance exercise program. Outcome variables were measured at baseline and endpoint.
Drop-out was 11.9% and not significantly different between genders. Drop-outs were significantly older and had poorer strength and physical function in comparison to completers. Anthropometrics, QoL, and cognitive function were not related to drop-out. According to multivariate analysis, gait speed and physical activity were the strongest predictors of drop-out. After the training, gains in lean mass or appendicular muscle were significantly higher in men than women; however relative gains in appendicular muscle as well as absolute improvements in strength and function were similar in men and women, respectively.
Participants who drop out are older, have poorer physical function, and are less physically active. Old women do not drop out more frequently than men and show meaningful improvements in relevant outcomes similar to men after such a training program. The trial is registered at the US National Library of Medicine (NCT01074879).
抗阻运动训练对肌肉减少症可能有效。我们确定了退出训练的预测因素,并比较了男性和女性在这种训练后的身体状况。
受试者( = 236名,73.7 ± 5.7岁)参加了为期12周的抗阻运动计划。在基线和终点测量结果变量。
退出率为11.9%,且性别间无显著差异。与完成训练者相比,退出者年龄显著更大,力量和身体功能更差。人体测量学、生活质量和认知功能与退出无关。根据多变量分析,步速和身体活动是退出的最强预测因素。训练后,男性的瘦体重或四肢肌肉增加显著高于女性;然而,男性和女性四肢肌肉的相对增加以及力量和功能的绝对改善分别相似。
退出训练的参与者年龄更大,身体功能更差,身体活动更少。老年女性并不比男性更频繁地退出训练,并且在这样一个训练计划后,她们在相关结果上显示出与男性相似的有意义的改善。该试验已在美国国立医学图书馆注册(NCT01074879)。