Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.
INSERM, Univ. Bordeaux, UMR1053 Bordeaux Research In Translational Oncology, BaRITOn, Bordeaux, France.
Helicobacter. 2017 Sep;22 Suppl 1. doi: 10.1111/hel.12409.
As Helicobacter pylori infects half the world's population and displays an extensive intraspecies diversity, genomics is a powerful tool to understand evolution and disease, to identify factors that confer higher risk of severe sequelae, and to find new approaches for therapy both among bacterial and host targets. In line with these objectives, this review article summarizes the major findings in Helicobacter genomics in papers published between April 2016 and March 2017.
由于幽门螺杆菌感染了全球一半的人口，并表现出广泛的种内多样性，基因组学是理解进化和疾病、识别导致严重后果风险更高的因素以及寻找细菌和宿主靶点治疗新方法的有力工具。本文综述了 2016 年 4 月至 2017 年 3 月间发表的关于幽门螺杆菌基因组学的主要研究成果。
