Davis Dawn Marie, Waldman Andrea, Jacob Sharon, LeBovidge Jennifer, Ahluwalia Jusleen, Tollefson Megha, Jetter Nathan, Spergel Jonathan
Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA.
Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, California, USA.
Semin Cutan Med Surg. 2017 Sep;36(3):95-99. doi: 10.12788/j.sder.2017.028.
Atopic dermatitis (AD) is a chronic inflammatory skin disease, with a remitting relapsing course. The central diagnostic features of AD include pruritus, xerosis, eczematous lesions with a characteristic morphology and distribution, and a personal or family history of atopic disease. Several clinical studies have emphasized the link between AD and other atopic disorders including asthma, allergic rhinitis, and food allergies. More recent studies indicate possible links between AD and other nonatopic disorders, including ADHD, sleep disturbance, and mental health disorders, suggesting an even more profound impact of this disease. Furthermore, the social, emotional, and personal impact of AD for patients and their caregivers is substantial. Understanding both the clinical characteristics and implications of AD is critical to lessening the psychosocial, clinical, and economic burden of this disease.
特应性皮炎（AD）是一种慢性炎症性皮肤病，病程呈缓解复发型。AD的主要诊断特征包括瘙痒、皮肤干燥、具有特征性形态和分布的湿疹样皮损，以及个人或家族特应性疾病史。多项临床研究强调了AD与其他特应性疾病之间的联系，包括哮喘、过敏性鼻炎和食物过敏。最近的研究表明，AD与其他非特应性疾病之间可能存在联系，包括注意力缺陷多动障碍（ADHD）、睡眠障碍和精神健康障碍，这表明该疾病的影响更为深远。此外，AD对患者及其照顾者的社会、情感和个人影响很大。了解AD的临床特征及其影响对于减轻该疾病的心理社会、临床和经济负担至关重要。
